Results 71 to 80 of about 1,549,315 (305)

Multi‐omics and low‐input proteomics profiling reveals dynamic regulation driving pluripotency initiation in early mouse embryos

FEBS Open Bio, EarlyView.
Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li, Xi Xiao, Lingbin Qi, Chanyi Li, Sirui Song, Jiaying Qin, Zhigang Xue, Jinfeng Xue, Huaifang Li   +8 more
wiley   +1 more source

Borrowed From the Future: Challenges and Guidelines for Community-Based Natural Resource Management [PDF]

, 2004
Identifies some of the obstacles that thwart the success of community-based programs, in a search for feasible solutions to the combined problems of environmental degradation and increasing human poverty and ...
Jason Clay
core  

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

FEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei, Fredrik Orädd, Konstantinos Magkakis, Magnus Andersson   +3 more
wiley   +1 more source

Impact of gold price, financial development, renewable energy, economic growth, urbanization, and environmental tax on environmental degradation

Frontiers in Environmental Science
This study comprehensively investigates the effects of gold price, financial development, renewable energy consumption, economic growth, urbanization, and environmental taxation on environmental degradation.
Prince Dorian Rivel Bambi, Jean Baptiste Bernard Pea-Assounga   +1 more
doaj   +1 more source

Biodegradation of the herbicide mecoprop-p with soil depth and its relationship with class III tfdA genes [PDF]

, 2010
Mecoprop-p [(R)-2-(4-chloro-2-methylphenoxy) propanoic acid) is widely used 37 in agriculture and poses an environmental concern because of its susceptibility to leach 38 from soil to water.
Alexander, Bending, Bending, Buss, Bælum, Bælum, Carsten S. Jacobsen, Environment Agency, European Environment Agency, Fomsgaard, Fredslund, Fulthorpe, Gary D. Bending, Helweg, Huong, Itoh, Itoh, Jacob Bælum, Johannesen, Johnson, Kitagawa, Kristensen, Lee, Liz J. Shaw, M Sonia Rodríguez-Cruz, McGowan, Parker, Pemberton, Reffstrup, Rodriguez-Cruz, Sakai, Sebastian R. Sørensen, Shaw, Shengjing Shi, Stanier, Suwa, Thomas Aspray, Tonso, Zakaria   +38 more
core   +1 more source

Erythropoietin modulates hepatic inflammation, glucose homeostasis, and soluble epoxide hydrolase and epoxides in high‐fat diet‐induced obese mice

FEBS Open Bio, EarlyView.
Erythropoietin administration suppresses hepatic soluble epoxide hydrolase (sEH) expression, leading to increased CYP‐derived epoxides. This is associated with a shift in hepatic macrophage polarization characterized by reduced M1 markers and increased M2 markers, along with reduced hepatic inflammation, suppressed hepatic lipogenesis, and attenuated ...
Takeshi Goda, Satoru Sugimoto, Chiharu Cho, Madoka Konishi, Nozomi Inoue, Satoshi Miyagaki, Yasuhiro Kawabe, Takuro Okamura, Masahide Hamaguchi, Hisakazu Nakajima, Michiaki Fukui, Masakazu Shinohara, Tomoko Iehara   +12 more
wiley   +1 more source

Soil Degradation and Contamination Due to Armed Conflict in Ukraine

Land
The impact of the active hostilities associated with Russia’s large-scale armed invasion of the territory of Ukraine on soil degradation as a result of military actions has resulted in soil damage due to heavy military armored vehicles.
Maksym Solokha, Olena Demyanyuk, Lyudmyla Symochko, Svitlana Mazur, Nadiya Vynokurova, Kateryna Sementsova, Ruslan Mariychuk   +6 more
doaj   +1 more source

Environmental degradation of claystones

Géotechnique, 2014
The paper presents the results of a comprehensive experimental programme carried out to study the effects of relative humidity cycling on the degradation of argillaceous rocks. Lilla claystone, a low-porosity Tertiary rock, was used for this purpose.
Pineda, J. A., Alonso, E. E., Romero, E.
openaire   +2 more sources

AGRICULTURE AND ENVIRONMENTAL POLICY: RECENT UNITED STATES AND AUSTRALIAN DEVELOPMENTS [PDF]

Agricultural development in both the United States and Australia has led to suboptimal levels of environmental degradation. While both countries face similar forms of agricultural environmental degradation, the different resource endowment and population
Hyberg, Bengt, Pascoe, Sean
core   +1 more source

Proteasomal degradation of intracellularly expressed Amblyomin‐X limits suicide gene therapy potential in melanoma cells

FEBS Open Bio, EarlyView.
This study explores the feasibility of expressing the antitumoral protein Amblyomin‐X through a suicide gene therapy approach and investigates its intracellular fate after gene delivery. Although the gene is efficiently expressed, melanoma cells rapidly degrade the Amblyomin‐X protein via proteasome activity.
Victor Dal Posolo Cinel, Carlos DeOcesano Pereira, Aline Ramos Maia Lobba, Melissa Regina Fessel, Ana Marisa Chudzinski‐Tavassi   +4 more
wiley   +1 more source