Results 51 to 60 of about 1,549,315 (305)

Pobreza rural e degradação ambiental: uma refutação da hipótese do círculo vicioso

Revista de Economia e Sociologia Rural, 2004
O estudo analisa as relações entre pobreza rural e degradação ambiental, tendo como área de estudo os municípios de Machadinho e Maximiliano de Almeida, na região Noroeste do RS. Com base nas entrevistas com 48 agricultores, foi formado um banco de dados,
Paulo D. Waquil, Marcus V. A. Finco, Ely J. Mattos   +2 more
doaj   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

CLIMATE CHANGE AND COMMUNITY ENVIRONMENTAL CONFLICTS: ARE THEY CORRELATED?

Sriwijaya Law Review, 2017
Climate change and global warming affect major change in freshwater availability and season uncertainty which hamper all part of the globe. Although the phenomenon is not new but it needs concerns from all the government of States around the world to ...
Achmad Romsan, Farida Ali, Akhmad Idris, Adrian Nugraha, Nurhidayatuloh Nurhidayatuloh, Suzanna Mohamed Isa   +5 more
doaj   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source

Dynamics of FDI, Technological Transformation and Environmental Degradation in Developing Countries: A Panel Analysis

Romanian Economic Journal, 2016
This paper examines the relationship between FDI, technology and environment with an assessment of aggregated relationship, by technical composition and the mode of technology transferability through FDI. A panel data for 19 developing countries has been
Farwa Amjad , Bilal Mehmood
doaj  

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

The Relationship Between Living Standards and Quality of Life: A Study of Urban Riverbank Settlements in Kotalama, Malang City

Jurnal Pembangunan dan Alam Lestari
Urbanization significantly transforms cities, introducing challenges affecting environmental sustainability and residents' quality of life. In urban riverbank settlements such as Kotalama, Malang City, these issues are compounded by inadequate planning ...
Erland Raziqin Fatahillah, Surjono Surjono, Abdul Wahid Hasyim, Mustika Anggraeni, Aurellia Parasti Jasmine   +4 more
doaj   +1 more source

Visible-light-driven Ag/Bi3O4Cl nanocomposite photocatalyst with enhanced photocatalytic activity for degradation of tetracycline [PDF]

, 2018
In this study, a novel Ag/Bi3O4Cl photocatalyst has been synthesized by a facile photodeposition process. Its photocatalytic performance was evaluated from the degradation of tetracycline (TC) under visible light irradiation (λ > 420 nm).
Che, Guangbo, Che, Huinan, Dong, Hongjun, Jiang, Enhui, Liu, Chunbo, Liu, Xiaoteng   +5 more
core   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

Molecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley, Michael W. Rohr, Joseph A. Goode, Sai Preethi Nakkina, Jignesh G. Parikh, Deborah A. Altomare   +5 more
wiley   +1 more source