Results 61 to 70 of about 892,850 (308)
Molecular Oncology, EarlyView.We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober +16 more
wiley +1 more source
Rapid assessment protocols of rivers as instruments of environmental education in elementary schools
Revista Ambiente & Água, 2017 The aim of the present study is to assess the use of rapid assessment protocols (RAPs) of rivers as environmental education (EE) instruments in elementary schools.
Ariane Guimarães +2 more
doaj +1 more source
What influences the emergence of a new subject in schools? The case of environmental education
, 2010 New subjects are always emerging but only some gain a place in the formal school curriculum. In fact, most of the now accepted conventional school subjects have, at some stage, struggled to become established. This paper presents findings of a three-year
Jones, Alister +3 more
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The Daily Planet: The Newsletter of the Alliance for New Jersey Environmental Education, Summer 2008
, 2008 This is the newsletter for Alliance for New Jersey Environmental Education (ANJEE), which is a privately supported, non-profit organization whose members are committed to using environmental education as an instrument for change in New Jersey. This issue
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Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
"Speculative Realism in Environmental Education and the Philosophy of Education" was a joint research symposium for the networks on Environmental and Sustainability Education (NW 30) and Philosophy of Education (NW 13), held at the European Conference of
Saari, Antti +17 more
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Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma
Molecular Oncology, EarlyView.Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski +10 more
wiley +1 more source
Transformación, 2018 The article approaches the need of given instruction on energy‐saving as a constituent of a comprehensive education al high school. The aim is to describe a developmental strategy, devised on the basis of specially tailored theoretical framework ...
Sonia Noa Delgado +2 more
doaj
Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer
Molecular Oncology, EarlyView.Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola +11 more
wiley +1 more source
Social Sciences and Humanities OpenAchieving sustainable development in Nigeria is inextricably linked to preserving the country's natural environment, species and biodiversity. However, human activities continue to degrade the natural environment, resulting in the loss of vital resources.
Anthony Kola-Olusanya +3 more
doaj +1 more source