Results 131 to 140 of about 2,199,922 (308)

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

Natural Disasters and the Environmental Along the U.S.-Mexico Border [PDF]

, 2008
Annual report of the U.S. Good Neighbor Environmental Board describing the organization's activities, goals, and recommendations for further development along the U.S.-Mexico border region.
United States. Good Neighbor Environmental Board.
core  

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

FEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi, João C. Encarnação, Valeria Napolitano, Grzegorz Dubin, Grzegorz Popowicz, Karl Andersson, U. Helena Danielson   +6 more
wiley   +1 more source

Effects of Ownership and Financial Status on Corporate Environmental Performance [PDF]

This paper analyzes the effects of ownership structure on corporate environmental performance and examines the link from financial performance to environmental performance in a transition economy.
Dietrich Earnhart, Lubomír Lízal
core  

A decade of children's environmental health research : highlights from EPA's Science to Achieve Results program / [PDF]

, 2007
health research.These 10 years of STAR research studies have shed light on how environmental exposures change from newborn to school-age children and on some of the genetic factors that contribute to children's vulnerability.
ICF International (Firm), National Center for Environmental Research (U.S.)   +1 more
core  

A Novel ISAR Image Feature Suppression Method Based on Arbitrary Phase Encoding

Remote Sensing
Compared with the amplitude modulation of conventional interrupted sampling repeater jamming (ISRJ), the image feature control method based on phase modulation exhibits greater energy efficiency and, therefore, has received wide attention recently.
Yanfeng Wang, Qihua Wu, Xiaobin Liu, Zhiming Xu, Feng Zhao, Shunping Xiao   +5 more
doaj   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

FEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj, Carolina Vazquez Garzon, Jose Joaquin Velasco, Janine N. Post   +3 more
wiley   +1 more source

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

FEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang, Hyo Been Jin, Chang Min Kim, So Yeon Lee, Hyun Ho Park   +4 more
wiley   +1 more source

Distributional Effects of Environmental and Energy Policy: An Introduction [PDF]

This chapter reviews literature on the distributional effects of environmental and energy policy. In particular, many effects of such policy are likely regressive.
Don Fullerton
core