Results 121 to 130 of about 2,199,922 (308)

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

Environmental effects of the Manganui ski field, Mt Taranaki/Egmont [PDF]

open access: yes, 2012
During May 2012, the environmental effects of the Manganui ski field were examined. Permanent quadrats first established in 1974 to monitor vegetation changes were re-measured, vegetation mapping was conducted, modifications to ground form and drainage ...
Bylsma, Rebecca Johanna   +2 more
core  

High-Resolution and Large-Scene Optical-SAR Registration via Star-UNet: A Local-to-Global Approach With Implicit Kernel Mapping

open access: yesIEEE Journal of Selected Topics in Applied Earth Observations and Remote Sensing
High-resolution, large-scene optical and SAR image registration is a fundamental task in remote sensing data processing, but it faces two main challenges: significant nonlinear radiometric differences and high computational costs.
Guo Qing   +4 more
doaj   +1 more source

Phosphoinositides and inositol phosphates as molecular glues

open access: yesFEBS Letters, EarlyView.
Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry   +9 more
wiley   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

open access: yesFEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee   +7 more
wiley   +1 more source

Production Effects of Agri-environmental Policy Measures: Reconciling Trade and Environmental Objectives [PDF]

open access: yes
In addition to generating commodity outputs, agricultural production activities affect water, air, and soil quality, influence eco-systems and biodiversity, and shape rural landscapes.
Peter Walkenhorst
core  

Short-term tests for carcinogens, mutagens, and other genotoxic agents / [PDF]

open access: yes, 1979
"July 1979.""United States Environmental Protection Agency, Health Effects Research Laboratory".Mode of access ...
Health Effects Research Laboratory (Research Triangle Park, N.C.)   +2 more
core  

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

open access: yesFEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

NNIP [PDF]

open access: yes
"In January 2001, the Pew Environmental Health Commission called for the creation of a coordinated public health system to prevent disease in the United States by tracking and combating environmental health threats. In response, the U.S.

core  

National Health and Environmental Effects Research Laboratory - An Annual Report for Accomplishments for Fiscal Year 2001 [PDF]

open access: yes, 2002
74 pages; available for download at the link below.This Annual Report showcases some of the scientific activities of the National Health and Environmental Effects Research Laboratory (NHEERL) in various health and environmental effects research areas ...
United States Environmental Protection Agency Office of Research and Development
core  

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