Results 101 to 110 of about 15,581,855 (303)

Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding

open access: yesFEBS Letters, EarlyView.
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança   +2 more
wiley   +1 more source

Short-term tests for carcinogens, mutagens, and other genotoxic agents /

open access: yes, 1979
"July 1979.""United States Environmental Protection Agency, Health Effects Research Laboratory".Mode of access ...
Health Effects Research Laboratory (Research Triangle Park, N.C.)   +2 more
core  

High-Resolution and Large-Scene Optical-SAR Registration via Star-UNet: A Local-to-Global Approach With Implicit Kernel Mapping

open access: yesIEEE Journal of Selected Topics in Applied Earth Observations and Remote Sensing
High-resolution, large-scene optical and SAR image registration is a fundamental task in remote sensing data processing, but it faces two main challenges: significant nonlinear radiometric differences and high computational costs.
Guo Qing   +4 more
doaj   +1 more source

Functional comparison of EncB and EncC cargo proteins in iron storage within the Myxococcus xanthus encapsulin

open access: yesFEBS Letters, EarlyView.
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell   +2 more
wiley   +1 more source

Natural Disasters and the Environmental Along the U.S.-Mexico Border

open access: yes, 2008
Annual report of the U.S. Good Neighbor Environmental Board describing the organization's activities, goals, and recommendations for further development along the U.S.-Mexico border region.
United States. Good Neighbor Environmental Board.
core  

Structural and biochemical analysis of a B12 superbinder

open access: yesFEBS Letters, EarlyView.
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices   +3 more
wiley   +1 more source

CDC's strategy for the National Environmental Public Health Tracking Program, fiscal years 2005-2010

open access: yes
"In January 2001, the Pew Environmental Health Commission called for the creation of a coordinated public health system to prevent disease in the United States by tracking and combating environmental health threats.

core  

The EPA Region 2 Environmental Justice Action Plan for Fiscal Years 2003 and 2004: New Jersey, New York, Puerto Rico, US Virgin Islands and 7 Tribal Nations

open access: yes, 2003
The EPA Region 2's Environmental Justice program is administered within the Office of the Regional Administrator. This report highlights the region's environmental justice actions which strive to ensure that no communities bear a disproportionate burden ...

core   +1 more source

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

open access: yesFEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

open access: yesFEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge   +6 more
wiley   +1 more source

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