Results 51 to 60 of about 5,408,281 (241)

Simulation analysis on return conductor configuration for lightning indirect effect test of metal cylinder

Zhongguo Jianchuan Yanjiu, 2019
[Objectives] In order to study the lightning indirect effect of metal cylindrical ordnance, a method for constructing the tester for lightning indirect effect of the metal cylindrical flying object is studied,and a cage type frame similar to coaxial line
HUANG Ruitao, DUAN Yantao, SHI Lihua, LUO Kang, ZHANG Qi   +4 more
doaj   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

FEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva, Ariann E. Mendoza‐Martínez, P. Abril Medina‐Flores, Carlos Campero‐Basaldua, Alexander DeLuna, Soledad Funes   +5 more
wiley   +1 more source

Exploring the potential mechanisms of anti-pulmonary fibrosis effects of Luo Han Guo via network pharmacology, molecular docking, and experimental validation

Scientific Reports
Idiopathic pulmonary fibrosis (IPF) is a chronic interstitial lung condition distinguished by a complex etiology, poor prognosis and exhibiting high mortality rates.
Qinlin Cui, Yingyi Liu, Yuxuan Li, Zhan Li, Wencai Wei, Simei Yang, Xin Liu, Lei Chen, Kunyu Xu, Yihan Li, Qingbi Zhang, Jun Bai   +11 more
doaj   +1 more source

Effect of crop management practices on the sustainability and environmental impact of organic and low input food production systems [PDF]

, 2007
While organic farming can reduce many of the environmental problems caused by agriculture, organic farming also includes some practices which are questionable in terms of environmental effects. Organic farming practices (rotations, fertilisation regimes,
Thorup-Kristensen, K.
core  

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

FEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li, Pedro A. Sánchez‐Murcia, Bernd Nidetzky   +2 more
wiley   +1 more source

Multiple components of environmental change drive populations of breeding waders in seminatural grasslands [PDF]

, 2018
Environments are rapidly changing due to climate change, land use, intensive agriculture, and the impact of hunting on predator populations. Here, we analyzed longterm data recorded during 1928–2014 on the size of breeding populations of waders at two ...
Asferg, Tommy, Balbontín Arenas, Javier, Haaning Nielsen, Henrik, Laursen, Karsten, Møller, Anders Pape, Thorup, Ole   +5 more
core   +4 more sources

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

FEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson, Mackenzie K Herroon, Shane Mecca, Laimar C Garmo, Jacob Lindquist, Shrila Rajendran, Steve M. Patrick, Izabela Podgorski   +7 more
wiley   +1 more source

All that is silver is not toxic: silver ion and particle kinetics reveals the role of silver ion aging and dosimetry on the toxicity of silver nanoparticles

Particle and Fibre Toxicology, 2018
Background When suspended in cell culture medium, nano-objects composed of soluble metals such as silver can dissolve resulting in ion formation, altered particle properties (e.g. mass, morphology, etc.), and modulated cellular dose.
Jordan N. Smith, Dennis G. Thomas, Hadley Jolley, Vamsi K. Kodali, Matthew H. Littke, Prabhakaran Munusamy, Donald R. Baer, Matthew J. Gaffrey, Brian D. Thrall, Justin G. Teeguarden   +9 more
doaj   +1 more source

Flexible blanket synthetic aperture radar jamming using joint frequency and phase modulation

IET Radar, Sonar & Navigation, 2023
Synthetic Aperture Radar (SAR) jamming is of vital significance in the national defence aspect. In this study, a flexible blanket jamming method against SAR is proposed using joint frequency and phase modulation.
Qihua Wu, Xiaobin Liu, Zhiming Xu, Feng Zhao, Zhaoyu Gu, Shunping Xiao   +5 more
doaj   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source