Results 101 to 110 of about 998,774 (300)

Handbook of environmental engineering assessment : strategy, planning, and management /

open access: yes, 2012
This is one of the most comprehensive books on complex subjects of environmental engineering assessment and planning. Addressing these issues requires an understanding of technical, economic, and policy perspectives; based upon extensive research and ...
Jain, Ravi
core  

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

open access: yesMolecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober   +16 more
wiley   +1 more source

Correspondence from Thomas E. McMullen (Service Environmental Engineering) to Rick Newquist (MPCA) re: Summary of Additional Investigation, Holman Building

open access: yes, 1997
Service Environmental Engineering; McMullen, Thomas E.. (1997). Correspondence from Thomas E. McMullen (Service Environmental Engineering) to Rick Newquist (MPCA) re: Summary of Additional Investigation, Holman Building.
Service Environmental Engineering   +1 more
core  

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

Life-cycle environmental engineering assessment of closed-loop recycling of automotive headlamp plastics based on LCC-LCA coupling [PDF]

open access: yesE3S Web of Conferences
From the perspective of environmental engineering, the high-value recovery and closed-loop recycling of plastics from end-of-life vehicles (ELVs) represent an important pathway for reducing solid-waste generation, resource consumption, and life-cycle ...
Meng Qingyao   +3 more
doaj   +1 more source

Novel coronavirus (COVID-19) in environmental engineering perspective. [PDF]

open access: yesEnviron Sci Pollut Res Int, 2022
Dehghani MH, Roy S, Karri RR.
europepmc   +1 more source

Evolutionary data division methods for developing artificial neural network models in geotechnical engineering

open access: yes, 2000
In recent years, artificial neural networks (ANNs) have been applied to many geotechnical engineering problems and have demonstrated some degree of success.
Shahin, Mohamed Amin   +2 more
core  

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

open access: yesMolecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim   +3 more
wiley   +1 more source

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