Results 121 to 130 of about 9,140,393 (327)

Editorial: New insight into the roles of microorganisms in municipal and environmental engineering technologies/systems. [PDF]

Front Microbiol, 2023
Chen X, Kasuga I, Liu X, Li H, Zeng M, Cai X.   +5 more
europepmc   +1 more source

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

Molecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala, Sini Ahonen, Sara Peltola, Aura Tuohisto‐Kokko, Olaya Esparta, Peppi Suominen, Anne Jokilammi, Iman Farahani, Deepankar Chakroborty, Nikol Dibus, Steffen Boettcher, Tomi T. Airenne, Mark S. Johnson, Lisa D. Eli, Klaus Elenius, Kari J. Kurppa   +15 more
wiley   +1 more source

Field Experiment to Evaluate the Phosphate Fertilizers Effect on Wheat' Morphological Traits [PDF]

Trends in Ecological and Indoor Environmental Engineering
Background: To meet SDG 2, agricultural productivity must double, and wheat production in particular must close the gap between demand and consumption.
Khalid Hussain Khokhar, Erdona Demiraj, Altaf Hussain Lahori, Mehrunisa Memon, Hafeezullah Babar, Saibrina Sethar , Muhammad Aslam Panhwar , Mahender Kumar , Zafar Ali Khokhar, Ambreen Afzal   +9 more
doaj   +1 more source

Inclusion of an Introduction to Infrastructure Course in a Civil and Environmental Engineering Curriculum [PDF]

, 2017
Civil infrastructure refers to the built environment (sometimes referred to as public works) and consists of roads, bridges, buildings, dams, levees, drinking water treatment facilities, wastewater treatment facilities, power generation and transmission ...
Behzad, Esmaeili, Hart, Steven D., Klosky, Led, Mayer, Brooke K., Parker, Philip J., Penn, Michael R.   +5 more
core   +1 more source

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source

Services Trade Negotiations in the Doha Round : Opportunities and Risks for Pakistan [PDF]

This paper seeks to examine how locking-in of Pakistans unilateral liberalization at the WTO/GATS and further liberalization of services trade would affect Pakistans competitiveness.
Abid A. Burki, S.M. Turab Hussain
core   +1 more source

Comparison of noise indicators in an urban context [PDF]

, 2016
Inter-Noise 2016, 45th International Congress and Exposition of Noise Control Engineering, HAMBOURG, ALLEMAGNE, 21-/08/2016 - 24/08/2016Noise is a major environmental issue, which gave birth in the last decades to the development of many engineering ...
Aumond, Pierre, Botteldooren, Dick, Can, Arnaud, De Coensel, Bert, Lavandier, Catherine, Michel, Sven, Ribeiro, Carlos   +6 more
core   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Novel coronavirus (COVID-19) in environmental engineering perspective. [PDF]

Environ Sci Pollut Res Int, 2022
Dehghani MH, Roy S, Karri RR.
europepmc   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

Molecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley, Michael W. Rohr, Joseph A. Goode, Sai Preethi Nakkina, Jignesh G. Parikh, Deborah A. Altomare   +5 more
wiley   +1 more source