Results 131 to 140 of about 998,774 (300)

Screening and epitope characterization of Nidogen‐2‐specific nanobodies

open access: yesFEBS Open Bio, EarlyView.
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen   +9 more
wiley   +1 more source

Quantitative proteomic analysis reveals different characteristics of bladder cancer cells after exposure to bisphenol A

open access: yesFEBS Open Bio, EarlyView.
Bisphenol A (BPA), a common chemical in plastics, exerts dual effects on bladder cancer cells: low doses promote growth and migration, while high doses suppress growth and migration. Multi‐omics and bioinformatics reveal BPA acts via MAPK and inflammatory pathways.
Shaomin Niu   +10 more
wiley   +1 more source

Proteasomal degradation of intracellularly expressed Amblyomin‐X limits suicide gene therapy potential in melanoma cells

open access: yesFEBS Open Bio, EarlyView.
This study explores the feasibility of expressing the antitumoral protein Amblyomin‐X through a suicide gene therapy approach and investigates its intracellular fate after gene delivery. Although the gene is efficiently expressed, melanoma cells rapidly degrade the Amblyomin‐X protein via proteasome activity.
Victor Dal Posolo Cinel   +4 more
wiley   +1 more source

THE ROLE OF GEOLOGY IN ENVIRONMENTAL ENGINEERING

open access: yesJournal of Chemists, Technologists and Environmentalists
Environmental engineering is an interdisciplinary science that relies on the knowledge of a number of other "basic" sciences - chemistry, mathematics, physics, biology and geology.
Dragana Dogančić   +1 more
doaj   +1 more source

Consultation on Information in Sanitary Engineering and Environmental Sciences : final report

open access: yes, 1977
Meeting: Consultation Group on Information in Sanitary Engineering and Environmental Sciences, 14-16 Nov.
Pan American Center for Sanitary Engineering and Environmental Sciences   +1 more
core  

Decreased cold‐sensing function of the transient receptor potential channel TRPM8 from tailed amphibians

open access: yesFEBS Open Bio, EarlyView.
Despite frogs avoiding low temperatures, examination of four salamander species revealed that none avoided cold and all possessed cold tolerance. Functional analysis of TRPM8, a cold sensor, showed that all salamander TRPM8s had lost their cold sensitivity.
Tadahiro Sawao   +3 more
wiley   +1 more source

Integrating Community Engagement and Service Learning into Environmental Engineering Curricula

open access: yesEducation Sciences
Engineering education is evolving to train students to work more closely with communities to support holistic sustainability. This has increasingly involved collaborative and participatory research models that address environmental justice challenges ...
Michelle Henderson   +4 more
doaj   +1 more source

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