Results 131 to 140 of about 8,455,634 (356)

Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

Molecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto, Nicolò Gualandi, Ylenia Cortolezzis, Raffaella Picco, Monica Colitti, Francesca D'Este, Mariachiara Gani, Wayne W. Hancock, Giovanni Terrosu, Cristina Degrassi, Francesca Agostini, Claudio Brancolini, Luigi E. Xodo, Eros Di Giorgio   +13 more
wiley   +1 more source

Islamic Environmental Systems Engineering [PDF]

, 1980
S. Waqar Ahmed Husaini
openalex   +1 more source

Investigating Environmental Health Engineering Graduates’ Attitudes towards Compliance of the Received Trainings with their Occupational Needs in Mashhad, Iran, 2019

, 2021
Roya Peirovi, Sara Javanbakht, Zohre Moeini, Monnavar Afzal Aghaee, Hossein Alidadi   +4 more
openalex   +2 more sources

Services Trade Negotiations in the Doha Round : Opportunities and Risks for Pakistan [PDF]

This paper seeks to examine how locking-in of Pakistans unilateral liberalization at the WTO/GATS and further liberalization of services trade would affect Pakistans competitiveness.
Abid A. Burki, S.M. Turab Hussain
core   +1 more source

Molecular characterisation of human penile carcinoma and generation of paired epithelial primary cell lines

Molecular Oncology, EarlyView.
Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad, Mahmood Hachim, Tom Bertin, Karolina Penderecka, Rifat Hamoudi, Saif Khan, Rui Henrique, Natalie Bergmoser, Manit Arya, Kalle Sipila, Matteo Vietri Rudan, Asif Muneer, Aamir Ahmed   +12 more
wiley   +1 more source

Recycled Materials in Civil and Environmental Engineering. [PDF]

Materials (Basel), 2022
Petrella A, Notarnicola M.
europepmc   +1 more source

Comparison of noise indicators in an urban context [PDF]

, 2016
Inter-Noise 2016, 45th International Congress and Exposition of Noise Control Engineering, HAMBOURG, ALLEMAGNE, 21-/08/2016 - 24/08/2016Noise is a major environmental issue, which gave birth in the last decades to the development of many engineering ...
Aumond, Pierre, Botteldooren, Dick, Can, Arnaud, De Coensel, Bert, Lavandier, Catherine, Michel, Sven, Ribeiro, Carlos   +6 more
core   +1 more source

Strength through diversity: how cancers thrive when clones cooperate

Molecular Oncology, EarlyView.
Intratumor heterogeneity can offer direct benefits to the tumor through cooperation between different clones. In this review, Kuiken et al. discuss existing evidence for clonal cooperativity to identify overarching principles, and highlight how novel technological developments could address remaining open questions.
Marije C. Kuiken, Maartje Witsen, Emile E. Voest, Krijn K. Dijkstra   +3 more
wiley   +1 more source

Cadmium (Cd) tolerance evaluation of three strains of microalgae of the genus Ankistrodesmus, Chlorella and Scenedesmus

Revista Facultad de Ingeniería Universidad de Antioquia, 2019
In order to assess tolerance to cadmium (Cd) for three Colombian native strains of microalgae belonging to the genus Ankistrodesmus, Chlorella and Scenedesmus the growth kinetics, the concentration of pigments, the total dry weight in media contaminated
D. Duque, C. Montoya, L. R. Botero
doaj  

Editorial: Emerging microbiological processes and tools that shine in pilot- and field-scale environmental engineering applications. [PDF]

Front Microbiol, 2023
Miao Y, Colosimo F, Mouser PJ, De Long S, Hanson Rhoades A.   +4 more
europepmc   +1 more source