Results 161 to 170 of about 8,455,634 (356)
Engineering needs environmental and global thinkers: a contextual analysis of student learning preferences [PDF]
, 2006 The need for engineering graduates who are environmentally and globally aware is now a recognised priority in professional practice. This paper presents an analysis of learning preferences of entry level students in a course which builds an early ...
Brumley, J, Buckeridge, J, Grundy, C
core
Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma
Molecular Oncology, EarlyView.Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken +7 more
wiley +1 more source
Engineering model test plan. Space storable propellant module environmental control technology [PDF]
Test program for engineering model of thermal control system of space storable propellant module in simulated ...
Haroldsen, O. O., Porter, R. N.
core +1 more source
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
Molecular Oncology, EarlyView.The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition
Molecular Oncology, EarlyView.We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li +10 more
wiley +1 more source
Material and Environmental Science, Building Engineering, Biomedical and Bioinformatics Technologies
, 2013 Huanyu Liu
openalex +1 more source
Switch on the bugs! (Where environmental engineering meets synthetic biology) [PDF]
, 2011 Rabaey, Korneel
core +2 more sources
Molecular Oncology, EarlyView.We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala +15 more
wiley +1 more source
GeotechnicsThis study investigates five cases of municipal solid waste (MSW) landfill slope failures in the USA, China, Sri Lanka, and Greece, with the aim of assessing the safety margins and reliability of these slopes.
Filip Dodigovic +3 more
doaj +1 more source