Results 71 to 80 of about 9,140,393 (327)

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

open access: yesFEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi   +5 more
wiley   +1 more source

Cleaner Production: The Key to Waste, Water and Energy Reduction in Higher Education, Philippines

open access: yesJPAIR, 2014
The fight against the worsening environmental problems has been the battle cry of the world. Environmental sustainability requires balance between development and the environment, is the key towards efficient resource management.
Richard A. Badiola   +3 more
doaj   +1 more source

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Measuring Impact of Uncertainty in a Stylized Macroeconomic Climate Model within a Dynamic Game Perspective

open access: yesEnergies, 2020
In this paper, we present a stylized dynamic interdependent multi-country energy transition model. The goal of this paper is to provide a starting point for examining the impact of uncertainty in such models. To do this, we define a simple model based on
Valentijn Stienen, Jacob Engwerda
doaj   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

Potentials for fisheries in the Niger Delta: Another green light for self sufficiency in regional food production [PDF]

open access: yes, 1985
A discussion is presented on the potential for fishery development in the Niger Delta region, considering engineering activities and food production potentials of the freshwater zone and immediate hinterland, the brackishwater mangrove swamps and the ...
Nalaguo, C.A.
core  

A methodology to introduce sustainability into the Final Year Project to foster sustainable engineering projects [PDF]

open access: yes, 2014
The introduction of sustainability skills into higher education curricula is a natural effect of the increasing importance of sustainability in our daily lives. Topics like green computing, sustainable design or environmental engineering have become part
Alier Forment, Marc   +7 more
core   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Study on Desulfurization Performance of FeCl3 Modified Activated Carbon

open access: yesKuangchan zonghe liyong
This is an essay in the field of environmental engineering. The experiment adopts the impregnation method, and uses FeCl3 as the modifier to modify the activated carbon to study its desulfurization ability. The effects of modifier concentration, roasting
Qian HU, Ran LIU, Jun ZHAO, Qing LYU
doaj   +1 more source

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