Results 31 to 40 of about 512,886 (252)

Hospitalization Through Families’ Eyes: Comparing Inpatient Care Quality for Children With Sickle Cell Disease and Cystic Fibrosis in Canada

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Sickle cell disease (SCD) is a chronic, inherited hemoglobinopathy that requires frequent hospitalization for disease‐related complications. Canadian data on inpatient care is limited. This study compared caregiver‐reported hospital experiences of children with SCD to those with cystic fibrosis (CF), a chronic, autosomal recessive ...
Hailey M. Zwicker, Kyle Kemp, Perri Tutelman, Sharon H. J. Hou, Paul Fairie, Maria Santana, Gregory M. T. Guilcher, Taryn Fay‐McClymont, Glenda Bendiak, Wendy Pelletier, Nicola Wright, Fiona Schulte   +11 more
wiley   +1 more source

Military environmental exposures and risk of breast cancer in active-duty personnel and veterans: a scoping review

Frontiers in Oncology
BackgroundThe effects of military environmental exposures (MEE) such as volatile organic compounds (VOCs), endocrine-disrupting chemicals (EDCs), tactile herbicides, airborne hazards and open burn pits (AHOBP), and depleted uranium on health are salient ...
Dylan J. Jester, Mehret T. Assefa, Daya K. Grewal, Daya K. Grewal, Abou M. Ibrahim-Biangoro, Abou M. Ibrahim-Biangoro, Jennifer S. Jennings, Jennifer S. Jennings, Maheen M. Adamson, Maheen M. Adamson   +9 more
doaj   +1 more source

Leveraging Epidemiology to Improve Risk Assessment. [PDF]

, 2011
The field of environmental public health is at an important crossroad. Our current biomonitoring efforts document widespread exposure to a host of chemicals for which toxicity information is lacking.
Burke, Thomas A, Fox, Mary A, Nachman, Keeve E, Rodricks, Joseph V, Sheehan, Mary C, Woodruff, Tracey J   +5 more
core  

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

Molecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera, Laura Vela‐Martín, Pablo Fernández‐Navarro, José Luis López‐Lorenzo, Javier Cornago, Pilar Llamas, Eduardo Pérez‐Gómez, José Luis Marín‐Rubio, Manuel Fresno, Javier Santos, José Fernández‐Piqueras, María Villa‐Morales   +11 more
wiley   +1 more source

Differential Genotyping of Mycobacterium avium Complex and Its Implications in Clinical and Environmental Epidemiology

Microorganisms, 2020
In recent decades, the incidence and prevalence of nontuberculous mycobacteria (NTM) have greatly increased, becoming a major worldwide public health problem.
Jeong-Ih Shin, Sung Jae Shin, Min-Kyoung Shin   +2 more
doaj   +1 more source

Environmental epidemiology: An introduction [PDF]

, 2016
Epidemiology is increasingly coping with problems correlated with exposures which may have small relative risks. In fact, many chronic diseases, as the most recent common diseases all over the world, may have unknown etiology but also potentially related
Amiri, Masoud., Arbabi, Mohsen.
core   +1 more source

Molecular cancer prevention: Intercepting disease

Molecular Oncology, EarlyView.
Oncological practice must evolve, from treating established tumours to proactive cancer interception before clinical manifestation. This will require mechanistic insight into tumour initiation, validated biomarkers of early disease development and redesigned clinical trials, enabling cancer interception to become a core pillar of oncology with the ...
Charlotte Grieco, Tej Pandya, Charles Swanton   +2 more
wiley   +1 more source

Association between historical lead exposure, population density, and autism prevalence: a county-level ecological study in Norway

Frontiers in Neuroscience
BackgroundAutism spectrum disorder (ASD) prevalence has increased markedly across high-income countries, including Norway, yet environmental drivers remain poorly understood.
Aaron Grossman
doaj   +1 more source

Geographical and temporal weighted regression (GTWR) [PDF]

, 2015
Both space and time are fundamental in human activities as well as in various physical processes. Spatiotemporal analysis and modeling has long been a major concern of geographical information science (GIScience), environmental science, hydrology ...
Andrienko, Artelaris, Atkinson, Bitter, Brunsdon, Brunsdon, Brunsdon, Buyantuyev, Chen, Comber, Crespo, Cressie, Cressie, Demšar, Elhorst, Fotheringham, Fotheringham, Fotheringham, Gelfand, Giacinto, Goodchild, Harris, Huang, Hägerstrand, Kwan, Kwan, Malczewskia, Mennis, Nakaya, Nakaya, Pace, Pace, Rey, Takahashi, Tobler, Wheeler, Wrenn, Wu, Wu, Yu   +39 more
core   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

FEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point, Wafaa Achache, Janïs Laudouze, Eliana Sepulveda Ramos, Mickaël Maziero, Céline Crauste, Stéphane Canaan, Pierre Santucci   +7 more
wiley   +1 more source