Results 91 to 100 of about 7,641,268 (406)

Unraveling Mycobacterium tuberculosis acid resistance and pH homeostasis mechanisms

FEBS Letters, EarlyView.
Mycobacterium tuberculosis exhibits a remarkable resilience to acid stress. In this Review, we discuss some of the molecular mechanisms and metabolic pathways used by the tubercle bacilli to adapt and resist host‐mediated acid stress. Mycobacterium tuberculosis (Mtb) is a successful pathogen that has developed a variety of strategies to survive and ...
Janïs Laudouze, Stéphane Canaan, Alexandre Gouzy, Pierre Santucci   +3 more
wiley   +1 more source

Prediction of the water solubility by a graph convolutional-based neural network on a highly curated dataset

Journal of Cheminformatics
Water solubility is a relevant physico-chemcial property in environmental chemistry, toxicology, and drug design. Although the water solubility is besides the octanol–water partition coefficient, melting point, and boiling point a property with a large ...
Nadin Ulrich, Karsten Voigt, Anton Kudria, Alexander Böhme, Ralf-Uwe Ebert   +4 more
doaj   +1 more source

Regional Air Quality Model Application of the Aqueous-Phase Photo Reduction of Atmospheric Oxidized Mercury by Dicarboxylic Acids

Atmosphere, 2013
In most ecosystems, atmospheric deposition is the primary input of mercury. The total wet deposition of mercury in atmospheric chemistry models is sensitive to parameterization of the aqueous-phase reduction of divalent oxidized mercury (Hg2+).
Jesse O. Bash, Annmarie G. Carlton, William T. Hutzell, O. Russell Bullock Jr.   +3 more
doaj   +1 more source

Simulating lightning NO production in CMAQv5.2: evolution of scientific updates [PDF]

Geoscientific Model Development, 2019
This work describes the lightning nitric oxide (LNO) production schemes in the Community Multiscale Air Quality (CMAQ) model. We first document the existing LNO production scheme and vertical distribution algorithm.
D. Kang, K. E. Pickering, D. J. Allen, K. M. Foley, D. C. Wong, R. Mathur, S. J. Roselle   +6 more
doaj   +1 more source

Biological Effects of Human Exposure to Environmental Cadmium

Biomolecules, 2022
Cadmium (Cd) is a toxic metal for the human organism and for all ecosystems. Cd is naturally found at low levels; however, higher amounts of Cd in the environment result from human activities as it spreads into the air and water in the form of ...
M. Peana, Alessio Pelucelli, Christos T. Chasapis, S. Perlepes, V. Bekiari, S. Medici, M. Zoroddu   +6 more
semanticscholar   +1 more source

The power of microRNA regulation—insights into immunity and metabolism

FEBS Letters, EarlyView.
MicroRNAs are emerging as crucial regulators at the intersection of metabolism and immunity. This review examines how miRNAs coordinate glucose and lipid metabolism while simultaneously modulating T‐cell development and immune responses. Moreover, it highlights how cutting‐edge artificial intelligence applications can identify miRNA biomarkers ...
Stefania Oliveto, Nicola Manfrini, Stefano Biffo   +2 more
wiley   +1 more source

Immunoprevalence to Six Waterborne Pathogens in Beachgoers at Boquerón Beach, Puerto Rico: Application of a Microsphere-Based Salivary Antibody Multiplex Immunoassay

Frontiers in Public Health, 2017
Waterborne infectious diseases are a major public health concern worldwide. Few methods have been established that are capable of measuring human exposure to multiple waterborne pathogens simultaneously using non-invasive samples such as saliva.
Swinburne A. J. Augustine, Kaneatra J. Simmons, Tarsha N. Eason, Clarissa L. Curioso, Shannon M. Griffin, Timothy J. Wade, Alfred Dufour, G. Shay Fout, Ann C. Grimm, Kevin H. Oshima, Elizabeth A. Sams, Mary Jean See, Larry J. Wymer   +12 more
doaj   +1 more source

Measuring environmental fungal exposure [PDF]

Medical Mycology, 2005
Airborne fungi are ubiquitous in the environment and human exposure is inevitable. Such fungi differ greatly in their taxonomic, physical, ecological, behavioral, and pathogenic characteristics. Many strategies have evolved to sample, identify and interpret fungal exposure and their choice is determined by the hypotheses involved.
Brett James Green, Brett James Green, Euan R. Tovey   +2 more
openaire   +3 more sources

Kidney and heavy metals - The role of environmental exposure (Review).

Molecular Medicine Reports, 2017
Heavy metals are extensively used in agriculture and industrial applications such as production of pesticides, batteries, alloys, and textile dyes. Prolonged, intensive or excessive exposure can induce related systemic disorders. Kidney is a target organ
P. Lentini, L. Zanoli, A. Granata, S. Signorelli, P. Castellino, R. Dell'aquila   +5 more
semanticscholar   +1 more source

The cytoskeletal control of B cell receptor and integrin signaling in normal B cells and chronic lymphocytic leukemia

FEBS Letters, EarlyView.
In lymphoid organs, antigen recognition and B cell receptor signaling rely on integrins and the cytoskeleton. Integrins act as mechanoreceptors, couple B cell receptor activation to cytoskeletal remodeling, and support immune synapse formation as well as antigen extraction.
Abhishek Pethe, Tanja Nicole Hartmann
wiley   +1 more source