Results 91 to 100 of about 1,123,096 (314)
Weakening the nuclear envelope: Lamin B receptor in melanoma metastasis
Molecular Oncology, EarlyView.LBR‐driven nuclear fragility supports melanoma invasion. A: Melanocyte presents low LBR (Lamin B Receptor) levels, maintaining nuclear integrity and lamina‐chromatin tethering. B: During malignant progression, upregulation of LBR clusters at the INM (Inner Nuclear Membrane) during confined migration causes local lamina weakening and cholesterol ...
Francesca Lorenzini +1 more
wiley +1 more source
Scientific DataSince the initial release of the Chemical and Products Database (CPDat) in 2018, the United States Environmental Protection Agency has added a considerable amount of chemical exposure-related information to the database and has expanded its schema to ...
Sakshi Handa +11 more
doaj +1 more source
Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer
Molecular Oncology, EarlyView.Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola +11 more
wiley +1 more source
National Report on Human Exposure to Environmental Chemicals [Online database March 2022-]
Overview: The National Report on Human Exposure to Environmental Chemicals (Report) presents nationally representative, cumulative biomonitoring data gathered since 1999\u20132000.In each survey period, the reported chemicals or their metabolites were ...
core +1 more source
Polybrominated Diphenyl Ether (PBDE) Serum Concentrations in Italian Women of Reproductive Age
ToxicsThe evaluation of human exposure to environmental contaminants is a highly relevant topic for carrying out appropriate risk assessments and management. For this reason, although exposure assessment studies are continuously increasing, it is important to ...
Annalisa Abballe +7 more
doaj +1 more source
Risk management for waterborne pathogens in public swimming pools: A pilot study
, 2006 There have been numerous reports of swimming pool-associated outbreaks of Cryptosporidiosis and Giardiasis worldwide, including Australia. It is essential to ensure that effective measures are in place to manage faecal contamination incidents, the ...
McManus, Alexandra +4 more
core
Molecular Oncology, EarlyView.Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim +3 more
wiley +1 more source
Frontiers in Public HealthIntroductionChildren and adolescents play an exceptional role in our society especially when it comes to safeguarding their health and given their higher susceptibility to environmental risk factors and ongoing physical development.MethodWe used data ...
Myriam Tobollik +3 more
doaj +1 more source
Environment International, 2018 Bisphenol A (BPA) is commonly manufactured to make polycarbonate plastics and epoxy resins for use in consumer products and packaged goods. BPA has been found in several different types of environmental media (e.g., food, dust, and air).
Marsha K. Morgan +5 more
doaj +1 more source
Occupational exposure to malathion [PDF]
"Criteria document giving recommendations for an occupational exposure standard for malathion (121755). Recommendations are made in respect of environmental, medical, labeling and posting, protection, information, work practices, sanitation, monitoring ...
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