Results 91 to 100 of about 6,134,553 (262)

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

FEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

4th National report on human exposure to environmental chemicals

The Fourth National Report on Human Exposure to Environmental Chemicals, 2009 (the Report) provides an ongoing assessment of the exposure of the U.S. population to environmental chemicals by the use of biomonitoring.

core   +1 more source

National Report on Human Exposure to Environmental Chemicals [Online database March 2022-]

Overview: The National Report on Human Exposure to Environmental Chemicals (Report) presents nationally representative, cumulative biomonitoring data gathered since 1999\u20132000.In each survey period, the reported chemicals or their metabolites were ...

core   +1 more source

The Chemical and Products Database v4.0, an updated resource supporting chemical exposure evaluations

Scientific Data
Since the initial release of the Chemical and Products Database (CPDat) in 2018, the United States Environmental Protection Agency has added a considerable amount of chemical exposure-related information to the database and has expanded its schema to ...
Sakshi Handa, Kristin K. Isaacs, Jonathan T. Wall, Allison Larger, Scott Burns, Lauren E. Koval, Kenta Baron-Furuyama, Colleen M. Elonen, David Lyons, Kathie L. Dionisio, M. Beth Horton, Katherine A. Phillips   +11 more
doaj   +1 more source

Estimating the environmental burden of disease in children and adolescents in Germany: limitations and possible solutions

Frontiers in Public Health
IntroductionChildren and adolescents play an exceptional role in our society especially when it comes to safeguarding their health and given their higher susceptibility to environmental risk factors and ongoing physical development.MethodWe used data ...
Myriam Tobollik, Sarah Kienzler, Dirk Wintermeyer, Dietrich Plass   +3 more
doaj   +1 more source

L‐aspartate oxidase provides new insights into fumarate reduction in anaerobic darkness in Synechocystis sp. PCC6803

FEBS Letters, EarlyView.
Synechocystis strains deficient in succinate dehydrogenase (SDH) secrete more succinate than the WT under dark anaerobic conditions, supporting that SDH then primarily acts as SDH, not as a fumarate reductase. L‐aspartate oxidase (Laspo) from Synechocystis is functional under anaerobic conditions, reducing fumarate to succinate.
Kateryna Kukil, Jeffrey A. Hawkes, Cecilia Blikstad, Pia Lindberg   +3 more
wiley   +1 more source

ExO: An Ontology for Exposure Science [PDF]

, 2011
An ontology is a formal representation of knowledge within a domain and typically consists of classes, the properties of those classes, and the relationships between them.
Carolyn Mattingly, Judith Blake, Judith Blake, Carolyn J. Mattingly, Elaine A. Cohen Hubal, Elaine Cohen Hubal, Thomas E. McKone, Michael Callahan, Thomas McKone   +8 more
core   +1 more source

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure−function relationships and relevance to human pathology

FEBS Letters, EarlyView.
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise, Tiziano Mazza, Raffaella Scanga, Lara Console, Michele Galluccio, Cesare Indiveri   +5 more
wiley   +1 more source

Risk management for waterborne pathogens in public swimming pools: A pilot study

, 2006
There have been numerous reports of swimming pool-associated outbreaks of Cryptosporidiosis and Giardiasis worldwide, including Australia. It is essential to ensure that effective measures are in place to manage faecal contamination incidents, the ...
McManus, Alexandra, East, J., Devine, B., Bertolatti, Dean, Weinstein, P.   +4 more
core  

Evaluation of exposure to arsenic in residential soil. [PDF]

, 2005
In response to concerns regarding arsenic in soil from a pesticide manufacturing plant, we conducted a biomonitoring study on children younger than 7 years of age, the age category of children most exposed to soil.
Eric A. Crecelius, Scrafford, Carolyn G, Barraj, Leila M, Leila M. Barraj, Pamela J. Mink, Michael Goodman, Van Kerkhove, Maria D, Kaetzel, Rhonda S, Maria D. Van Kerkhove, Goodman, Michael, Rhonda S. Kaetzel, Joyce S. Tsuji, Tsuji, Joyce S, Mink, Pamela J, Carolyn G. Scrafford, Crecelius, Eric A   +15 more
core   +1 more source