Results 101 to 110 of about 2,506,056 (353)

The Chemical and Products Database v4.0, an updated resource supporting chemical exposure evaluations

open access: yesScientific Data
Since the initial release of the Chemical and Products Database (CPDat) in 2018, the United States Environmental Protection Agency has added a considerable amount of chemical exposure-related information to the database and has expanded its schema to ...
Sakshi Handa   +11 more
doaj   +1 more source

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

open access: yesMolecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici   +8 more
wiley   +1 more source

Distribution, variability, and predictors of urinary bisphenol A levels in 50 North Carolina adults over a six-week monitoring period

open access: yesEnvironment International, 2018
Bisphenol A (BPA) is commonly manufactured to make polycarbonate plastics and epoxy resins for use in consumer products and packaged goods. BPA has been found in several different types of environmental media (e.g., food, dust, and air).
Marsha K. Morgan   +5 more
doaj   +1 more source

Environmental Exposure in Lebanese Infants (EELI): A Longitudinal Birth Cohort- Pilot Study

open access: diamond, 2021
Myriam Mrad Nakhlé   +6 more
openalex   +1 more source

Simple traffic measures significantly reduce the exposure of primary school children to NO2 [PDF]

open access: yes, 2019
According to Public Health England (PHE, 2019) air quality is the largest environmental health risk in the UK; long-term exposure to air pollution claims some 28-36,000 premature deaths each year.
Cameron, Valerie   +3 more
core  

PYCR1 inhibition in bone marrow stromal cells enhances bortezomib sensitivity in multiple myeloma cells by altering their metabolism

open access: yesMolecular Oncology, EarlyView.
This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert   +13 more
wiley   +1 more source

Environmental exposure effects on composite materials for commercial aircraft [PDF]

open access: yes
The effects of environmental exposure on composite materials are studied. The environments considered are representative of those experienced by commercial jet aircraft.
Gibbins, M. N., Hoffman, D. J.
core   +4 more sources

Association of Environmental Exposures in Pregnancy and Early Life with Islet Autoimmunity Development in Children in Bavaria, Germany

open access: green, 2022
Mahnaz Badpa   +6 more
openalex   +1 more source

Inhibition of CDK9 enhances AML cell death induced by combined venetoclax and azacitidine

open access: yesMolecular Oncology, EarlyView.
The CDK9 inhibitor AZD4573 downregulates c‐MYC and MCL‐1 to induce death of cytarabine (AraC)‐resistant AML cells. This enhances VEN + AZA‐induced cell death significantly more than any combination of two of the three drugs in AraC‐resistant AML cells.
Shuangshuang Wu   +18 more
wiley   +1 more source

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