Results 131 to 140 of about 6,134,553 (262)

Update on EPA lead mapping efforts to identify locations at higher risk of lead exposure [PDF]

EPA-mapping-efforts-locations-high-risk-lead-exposure-Dec-LEPAC-508 ...

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Spatial biology in cancer epigenetics

Molecular Oncology, EarlyView.
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley   +1 more source

Lead Exposure and Prevention Advisory Committee (LEPAC) : 2020 annual report to U.S. Department of Health and Human Services [PDF]

The objective of the Lead Exposure and Prevention Advisory Committee (LEPAC) is to review research andFederal programs and services related to lead poisoning and to identify effective services and best practices for addressing and preventing lead ...

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Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

Molecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche, Niels J. van Ruitenbeek, Charlotte Adang, Luke O'Gorman, Pui Yuen Lee, Willemijn M. Klein, Adriana C. H. van Engen‐van Grunsven, Jack A. Schalken, Sander Bervoets, Gerald W. Verhaegh, Carla M. L. van Herpen   +10 more
wiley   +1 more source

Prenatal exposure to environmental contaminants and cord serum metabolite profiles in future immune-mediated diseases

BACKGROUND: Prenatal exposure to environmental contaminants is a significant health concern because it has the potential to interfere with host metabolism, leading to adverse health effects in early childhood and later in life.
Hyötyläinen, Tuulia,, Triplett, Eric,, Oresic, Matej,, Ludvigsson, Johnny,, Ghaffarzadegan, Tannaz,, Bagavathy Shanmugam, Karthikeyan,   +5 more
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Variability of environmental exposure to fine particles, black smoke, and trace elements among a Swedish population

, 2011
Mixed-effects models were used to estimate within-person and between-person variance components, and some determinants of environmental exposure to particulate matter (PM(2.5)), black smoke (BS) and trace elements (Cl, K, Ca, Ti, Fe, Ni, Cu, Zn, and Pb ...
Sällsten, Gerd,, Stephen M Rappaport, Rappaport, Stephen M, Gerd Sallsten, Sandra Johannesson, Johannesson, Sandra,   +5 more
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ADP‐ribosylation: An emerging regulator of the epigenome

Molecular Oncology, EarlyView.
ADP‐ribosylation has emerged as a dynamic epigenetic signaling mechanism that modifies histones and chromatin‐associated proteins. Through coordinated PARylation and MARylation, it integrates with other histone modifications to regulate chromatin structure, transcription factor activity, and gene expression, influencing genome function and disease ...
Cristel V. Camacho, Chenqian Liu, W. Lee Kraus   +2 more
wiley   +1 more source

Mapping efforts to identify populations at higher risk of lead exposure: HUD perspective [PDF]

HUD-mapping-efforts-populations-high-risk-lead-exposure-Dec-LEPAC-508 ...

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Preparation of Ti3C2Tx modified rare earth doped PbO2 electrodes for efficient removal of sulfamethoxazole

Scientific Reports
In this study, we deposited Ti3C2Tx-modified, rare-earth-doped PbO2 on the surface of a carbon fabric via electrodeposition. The surface morphology and electronic structure of the electrode were characterized with SEM, XRD and XPS.
Dancheng Zhu, Yifan Wu, Kai Zheng, Hao Xu, Chao Chen, Jun Qiao, Chao Shen   +6 more
doaj   +1 more source

Arginine methylation as a regulatory ratchet in cancer: From substrate selection to malignant‐state stabilization

Molecular Oncology, EarlyView.
Arginine methylation can be viewed as a persistence‐prone post‐translational modification regulated by a network of PRMTs. Competitive and compensatory interactions among PRMTs can redistribute methylation across substrate pools shaped by sequence, structural, spatial, and environmental layers, reinforcing RNA‐processing, chromatin, and signaling ...
So Hyun Kwon, Ji Min Lee
wiley   +1 more source