Results 201 to 210 of about 2,506,056 (353)

Rethinking Strategies for a Pharmaceutical Approach to Pain Related to Connective Tissue–Related Raynaud Phenomenon in the United States

Arthritis Care &Research, EarlyView.
Objective There are no US Food and Drug Administration–approved therapies for Raynaud phenomenon (RP) in the United States. Clinical trials have been challenged by study design. Important advances in RP patient‐reported outcome measures and mechanistic quantification allow RP‐related pain characterization.
Tracy M. Frech, Charles G. Frech, W. David Merryman, Andrew Sternlicht, Justin Baba   +4 more
wiley   +1 more source

A systems immunology analysis of Alzheimer's disease reveals an age- and environmental exposure-independent disturbance in B cell maturation. [PDF]

Alzheimers Dement
Humblet-Baron S, Feng Y, Veiga R, Neumann J, Prezzemolo T, Pasciuto E, Vandenberghe R, Yshii L, Liston A.   +8 more
europepmc   +1 more source

Reference values and exposure risk of bisphenol A and its substitutes in Taiwan: Taiwan environmental survey for Toxicants (TESTs) 2013–2016

Hsin-Chang Chen, Jung-Wei Chang, Yu-Jung Lin, Wan-Ting Chang, Hsin-I Huang, Cai Yu-chen, Po-Chin Huang   +6 more
openalex   +1 more source

Metabolic shift in lung alveolar cell mitochondria after exposure to environmental toxicants

, 2013
Amit Agarwal
openalex   +1 more source

A Qualitative Analysis of Patient Perspectives and Preferences in Lupus Management to Guide Lupus Guidelines Development

Arthritis Care &Research, EarlyView.
Objective A patient‐centered approach for chronic disease management, including systemic lupus erythematosus (SLE), aligns treatment with patients’ values and preferences, leading to improved outcomes. This paper summarizes how patient experiences, perspectives, and priorities informed the American College of Rheumatology (ACR) 2024 Lupus Nephritis (LN)
Shivani Garg, Izzy Hartel, Lisa R. Sammaritano, Anca Askanase, Bonnie L. Bermas, Maria Dall'Era, Alí Duarte‐García, Victoria P. Werth, Brad Rovin, Reem A. Mustafa, Amy S. Turner, Bené Williams, Brian L. Ung, Hiya Bhavsar, Monique C. Gore‐Massy, Nahirannette Pulido, Natacha Guerrero, Natalie M. Smith, Wambui Machua, Linda T. Hiraki, Mary Beth Son   +20 more
wiley   +1 more source

Microplastics as an emerging driver of osteoarthritis: a translational synthesis of environmental exposure, patho-mechanisms, and public health implications. [PDF]

J Transl Med
Malik MA, Wu S, Zhang W, Huang J, Cao X, Ayub U, Malik A.   +6 more
europepmc   +1 more source

Human benzene metabolism following occupational and environmental exposures

, 2020
Stephen M. Rappaport, Sungkyoon Kim, Qing Lan, Guilan Li, Roel Vermeulen, Suramya Waidyanatha, Luoping Zhang, Songnian Yin, Martyn T. Smith, Nathaniel Rothman   +9 more
openalex   +1 more source

β‐Catenin/c‐Myc Axis Modulates Autophagy Response to Different Ammonia Concentrations

Advanced Biology, Volume 9, Issue 3, March 2025.
Ammonia, detoxified by the liver into urea and glutamine, impacts autophagy differently at varying levels. Low ammonia activates autophagy via c‐Myc and β‐catenin, while high levels suppress it. Using Huh7 cells and Spf‐ash mice, c‐Myc's role in cytoprotective autophagy is revealed, offering insights into hyperammonemia and potential therapeutic ...
S. Sergio, B. Spedicato, G. Corallo, A. Inguscio, M. Greco, D. Musarò, D. Vergara, A. F. Muro, G. De Sabbata, L. R. Soria, N. Brunetti Pierri, M. Maffia   +11 more
wiley   +1 more source

Sources of Environmental Exposure to the Naturally Occurring Anabolic Steroid Ecdysterone in Horses. [PDF]

Animals (Basel)
Sillence MN, Holt K, Li FI, Harris PA, Coyle M, Fitzgerald DM.   +5 more
europepmc   +1 more source

Enhancing Corrosion Resistance and Mechanical Strength of 3D‐Printed Iron Polylactic Acid for Marine Applications via Laser Surface Texturing

Advanced Engineering Materials, EarlyView.
Laser surface texturing significantly improves the corrosion resistance and mechanical strength of 3D‐printed iron polylactic acid (Ir‐PLA) for marine applications. Optimal laser parameters reduce corrosion by 80% and enhance tensile strength by 25% and ductility by 15%.
Mohammad Rezayat, Mojtaba Karamimoghadam, Mohammadreza Lalegani Dezaki, Ali Zolfagharian, Giuseppe Casalino, Antonio Mateo, Mahdi Bodaghi   +6 more
wiley   +1 more source