Results 1 to 10 of about 1,827,691 (322)

Contribution of hippocampal BDNF/CREB signaling pathway and gut microbiota to emotional behavior impairment induced by chronic unpredictable mild stress during pregnancy in rats offspring [PDF]

PeerJ, 2022
Background Numerous studies have shown that exposure to prenatal maternal stress (PMS) is associated with various psychopathological outcomes of offspring. The accumulating evidence linking bacteria in the gut and neurons in the brain (the microbiota-gut-
Feng Zhao, Kai Wang, Yujun Wen, Xiaohui Chen, Hongya Liu, Faqiu Qi, Youjuan Fu, Jiashu Zhu, Suzhen Guan, Zhihong Liu   +9 more
doaj   +2 more sources

Environmental Factors and Endometriosis [PDF]

International Journal of Environmental Research and Public Health, 2021
Endometriosis is a common disease, affecting up to 60–80% of women, with pelvic pain or/and infertility. Despite years of studies, its pathogenesis still remains enigmatic. Genetic, hormonal, environmental, and lifestyle-related factors may be involved in its pathogenesis. Thus, the design of the review was to discuss the possible role of environmental
Grzegorz Polak, Beata Banaszewska, Michał Filip, Michał Radwan, Artur Wdowiak   +4 more
openaire   +2 more sources

Environmental Factors

Critical Care Clinics, 2021
The acute respiratory distress syndrome (ARDS) remains a major cause of morbidity and mortality in the intensive care unit. Improving outcomes depends on not only evidence-based care once ARDS has already developed but also preventing ARDS incidence. Several environmental exposures have now been shown to increase the risk of ARDS and related adverse ...
Wick, Katherine D, Matthay, Michael A
openaire   +4 more sources

Epigenetics in neurodegenerative disorders induced by pesticides

Genes and Environment, 2021
Neurodegenerative diseases are becoming major socio-economic burdens. However, most of them still have no effective treatment. Growing evidence indicates excess exposure to pesticides are involved in the development of various forms of neurodegenerative ...
Guangxia Yu, Qianqian Su, Yao Chen, Lingyan Wu, Siying Wu, Huangyuan Li   +5 more
doaj   +1 more source

Transcriptomic profiles of paraquat-induced Parkinson-like changes in mouse brains based on single-cell RNA sequencing

环境与职业医学, 2023
BackgroundParaquat (PQ) is one of the most widely used herbicides in the world and a risk factor for Parkinson's disease (PD), but the mechanisms underlying PD are poorly understood.
Zhenkun GUO, Yating ZHANG, Yali WENG, Siying WU, Huangyuan LI   +4 more
doaj   +1 more source

Meta-analysis of effects of long-term exposure to PM2.5 on C-reactive protein levels

环境与职业医学, 2022
BackgroundFine particulate matter (PM2.5) is a serious air pollutant associated with elevated levels of C-reactive protein (CRP), an inflammatory indicator.ObjectiveTo assess the potential impacts of long-term exposure to PM2.5 on CRP levels based on ...
Yifei LIU, Suzhen GUAN, Haiming XU, Na ZHANG, Min HUANG, Zhihong LIU   +5 more
doaj   +1 more source

The mediation path of physical multimorbidity on the vulnerability to health-related poverty of rural aging families in Ningxia, China: A cross-sectional survey

Frontiers in Public Health, 2022
BackgroundVulnerability to health-related poverty can predict the probability of families falling into poverty due to health risk impact. In this study, we measured the vulnerability to health-related poverty and examined the mediation path of physical ...
Wenqin Guo, Wenqin Guo, Jiancai Du, Jiancai Du, Kexin Chen, Kexin Chen, Wenlong Wang, Wenlong Wang, Baokai Gao, Baokai Gao, Zhaoyan Hu, Zhaoyan Hu, Hui Qiao, Hui Qiao   +13 more
doaj   +1 more source

Mechanism of miR-21 targeting Smad7 in pulmonary fibrosis of A549 cells induced by beryllium sulfate

环境与职业医学, 2022
BackgroundThe pathogenesis of beryllium-induced pulmonary fibrosis is unknown and there is no specific treatment for the disease as yet. MicroRNA (miRNA) may play a role in the process of beryllium-induced pulmonary fibrosis.ObjectiveTo construct a ...
Faqiu QI, Xiaohui CHEN, Hongya LIU, feng ZHAO, Youjuan FU, Suzhen GUAN, Kai WANG   +6 more
doaj   +1 more source

Development and Applications of an In Situ Probe for Multi-Element High-Resolution Measurement at Soil/Sediment-Water Interface and Rice Rhizosphere

Agronomy, 2021
The biogeochemistry of multi-elements, such as sulfur (S), phosphorus (P) and arsenic (As), is interlinked especially at interfaces of soil/sediment–water and plant rhizosphere.
Meng Zhao, Jiang Liu, Chuangchuang Zhang, Xuefeng Liang, Qian E, Rongle Liu, Yujie Zhao, Xiaowei Liu   +7 more
doaj   +1 more source

MicroRNAs of Human Herpesvirus 6A and 6B in Serum and Cerebrospinal Fluid of Multiple Sclerosis Patients

Frontiers in Immunology, 2020
Human herpesvirus-6A (HHV-6A) and −6B (HHV-6B) might be involved in the etiopathogenesis of multiple sclerosis (MS), especially the HHV-6A. We aim at assessing, for the first time in the scientific literature, the HHV-6A/B microRNAs in MS patients.
María I. Domínguez-Mozo, Alejandro Nieto-Guerrero, Silvia Pérez-Pérez, María Á. García-Martínez, Rafael Arroyo, Roberto Álvarez-Lafuente   +5 more
doaj   +1 more source