Results 121 to 130 of about 5,640,250 (316)

Nicotinamide N‐methyltransferase promotes drug resistance in lung cancer, as revealed by nascent proteomic profiling

Molecular Oncology, EarlyView.
AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou, Zhen Wang, Fei Yang, Xiao Han, Lei Li, Huadong Liu   +5 more
wiley   +1 more source

Association between cooking with solid fuels and depressive symptoms among middle-aged and older adults in China: The mediating effect of the residential environment

Ecotoxicology and Environmental Safety
Background: Depression is a common issue among elderly people in both developing and developed countries. Existing research indicates that cooking with solid fuels has a negative impact on the mental health of middle-aged and elderly people (aged 45 and ...
Ximin Ma, Jiahui He, Qi Hu, Wenlong Wang, Hui Qiao   +4 more
doaj   +1 more source

Author response for "Temporal beta diversity of lake plants is determined by concomitant changes in environmental factors across decades"

, 2020
Marja Lindholm, Janne Alahuhta, Jani Heino, Heikki Toivonen   +3 more
openalex   +1 more source

Remediation of Cr(VI)/Cd(ІІ)-Contaminated Groundwater with Simulated Permeable Reaction Barriers Filled with Composite of Sodium Dodecyl Benzene Sulfonate-Modified Maifanite and Anhydride-Modified Fe@SiO₂@Polyethyleneimine: Environmental Factors and Effectiveness [PDF]

, 2021
Jingqing Gao, Yalin Zhai, Zhenzhen Huang, Peng Ren, Jianlei Gao, Zhijun Chen, Shunling Li   +6 more
openalex   +1 more source

Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology

Molecular Oncology, EarlyView.
Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts, Senada Koljenović, Elise Daems, Karolien De Wael, Marc Peeters, Léon C. van Kempen, Greetje Vanhoutte, Karen Zwaenepoel, Timon Vandamme   +8 more
wiley   +1 more source

The blockage of the electron transport chains caused by PFOA isomers induced metabolic damage of Arabidopsis leaves

Environmental Chemistry and Ecotoxicology
Different metabolic damage could be caused by PFOA isomers, although the harm mechanism has not been well studied. The effects of PFOA isomers on Arabidopsis metabolism were investigated using metabolomics, proteomics and molecular docking.
Hao Wang, Jianxiong Mei, Zeying He, Bingjie Liu, Jishi Wang, Yue Geng, Yanwei Zhang   +6 more
doaj   +1 more source

Blended Value Investing: Integrating Environmental Risk and Opportunities into Securities Valuation [PDF]

, 2007
Increasingly, investors are integrating environmental risk and opportunity into their financial valuations of public and private assets. This paper offers an overview of how environmental factors might be integrated into companies' financial valuation ...
Jacob Harold, Jed Emerson, Joshua Spitzer   +2 more
core  

Comparison of Household Environmental Factors among Children with Reported Asthma and Controls [PDF]

, 2023
Joana Sousa
openalex   +1 more source

Adenosine‐to‐inosine editing of miR‐200b‐3p is associated with the progression of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira, Anna Skwarska, Karolina Chwialkowska, Agnieszka Ostrowska, Gabriela Sokolowska, Anna Zeller, Anna Erol, Andrzej Eljaszewicz, Bartosz Hanczaruk, Anna Michalska‐Falkowska, Agnieszka Tarasik, Joanna Reszec‐Gielazyn, Pawel Knapp, Marcin Moniuszko, Adam Kretowski   +14 more
wiley   +1 more source

The effects of selenium on the translation efficiency of selenoproteins GPX1, GPX4, and TXNRD1 in oxLDL-induced EA.hy926 cells

Food Science and Human Wellness
Selenium is a crucial trace element that contributes to physiological processes in the body as selenoproteins. Selenoproteins serve as an integral role in the body in controlling the redox state of cells and protecting against damage induced by oxidative
Jiaqi Lu, Jing Meng, Yanzhi Lang, Abdul Rehman, Yamei Yan, Linwu Ran   +5 more
doaj   +1 more source