Results 101 to 110 of about 863,612 (313)
Comparing Global Violations of Environmentally Critical Groundwater Discharge Thresholds
Water Resources ResearchGroundwater is a crucial resource to support surface water bodies via groundwater discharge. In this study, we applied two methods of estimating global environmentally critical groundwater discharge, defined as the flux of groundwater to streamflow ...
B. P. P. Marinelli +4 more
doaj +1 more source
Closing the yield gap while ensuring water sustainability
Environmental Research Letters, 2018 Water is a major factor limiting crop production in many regions around the world. Irrigation can greatly enhance crop yields, but the local availability and timing of freshwater resources constrains the ability of humanity to increase food production ...
Lorenzo Rosa +5 more
doaj +1 more source
Think Globally, Act Locally? Stock vs Flow Regulation of a Fossil Fuel [PDF]
Regulation of environmental externalities like global warming from the burning of fossil fuels (e.g., coal and oil) is often done by capping both emission flows and stocks. For example, the European Union and states in the Northeastern United States have
Amigues, Jean-Pierre +2 more
core
Molecular Oncology, EarlyView.In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera +11 more
wiley +1 more source
Enviromental patterns and intermittent cascades [PDF]
, 2017 Real environmental flows are non-homogeneous, of fundamental interest is to determine and quantify turbulent diffusion from the available conditions of the flow, because the role of buoyancy and rotation modify the flow topology with often the dominant ...
Carrillo Cortés, José Alejandro +4 more
core +1 more source
Molecular Oncology, EarlyView.Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau +8 more
wiley +1 more source
Impacts of Regulating Greenhouse Gas Emissions on Livestock Trade Flows [PDF]
The policies that regulate greenhouse gas emissions would provide a significant burden to emission industries as well as final consumers, which can lead to a strong influence on international trade flows of commodities.
Kim, Hyun Seok, Koo, Won W.
core +1 more source
Molecular Oncology, EarlyView.We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu +10 more
wiley +1 more source
Molecular Oncology, EarlyView.Translational cancer research and its implementation through competitively selected Comprehensive Cancer Centers across Europe should be the primary policy focus for addressing the increasing cancer burden in Europe and counteract the present main strategy to convert cancer to a chronic disease.
Manuel Heitor +2 more
wiley +1 more source
Checkpoint blockade and the stem‐like T cell trade‐off
Molecular Oncology, EarlyView.Stem‐like T cells are key to the success of programmed cell death protein 1 (PD1) blockade, as they sustain long‐term anti‐tumor response by continuously generating effector CD8+ T cells. However, how these cells are maintained in cancer is not fully understood. Hor et al.
Julie M. Mazet, Johanna A. Joyce
wiley +1 more source