Results 81 to 90 of about 863,612 (313)
Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Assessing SDG indicator 6.4.2 ‘level of water stress’ at major basins level
UCL Open Environment, 2021 This paper describes a method to disaggregate indicator 6.4.2 (level of water stress) by major river basins. The analysis was performed using the GlobWat soil water balance model and global geospatial data consistent with national statistics published in
doaj +2 more sources
Developing procedures for assessment of ecological status of Indian River basins in the context of environmental water requirements [PDF]
River basins / Ecology / Indicators / Environmental flows / Environmental management / Habitats / Biota / Fish / Ecosystems / India / Krishna River Basin / Chauvery River Basin / Narmada River Basin / Periyar River Basin / Ganga River ...
Arunachalam, M. +8 more
core
Dynamic Ecological System Analysis
, 2018 This article develops a new mathematical method for holistic analysis of nonlinear dynamic compartmental systems through the system decomposition theory.
Coskun, Huseyin
core +1 more source
Molecular Oncology, EarlyView.Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source
Applying and Assessing Participatory Approaches in an Environmental Flows Case Study. [PDF]
Environ Manage, 2023 Mussehl M +4 more
europepmc +1 more source
DEFINING THE 'SAVING' IN AGRICULTURE WATER WHEN IRRIGATION TECHNOLOGY IS A CHOICE VARIABLE: THE CASE OF THE KLAMATH BASIN [PDF]
Increasing demand for water in the environment has increased the cost of irrigation water in agriculture leading to the adoption of water saving irrigation technologies, reducing agricultural return flows.
Adams, Richard M., Burke, Susan M.
core +1 more source
Utilising the concept of nutrients as a currency within organic farming system [PDF]
, 2002 This report was presented at the UK Organic Research 2002 Conference.Within organic systems, the successful management of nutrients at the field level is crucial for maximising production and minimising the environmental impacts.
Stockdale, Elizabeth +2 more
core
Molecular Oncology, EarlyView.Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano +6 more
wiley +1 more source