Results 111 to 120 of about 820,522 (298)

Evaluation of the construction level and analysis of the spatio–temporal evolution pattern of ecological civilization in the Yellow River Basin

Sustainable Futures
The evaluation of ecological civilization is an effective tool for measuring a country's level of sustainable development. A comprehensive evaluation indicator system was constructed for the ecological civilization construction level (ECCL) in China's ...
Danyang FENG, Xiaojie MENG, Ranran YANG, Yingying CHAI, Yuefeng SHI, Mengyang GAO   +5 more
doaj   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source

The emancipatory inclusion of nonhuman animals in the Dutch sustainable food system transition: An embodied critical discourse analysis

Earth System Governance
There is increasing agreement among scientists and policy makers that we need transformative change, change at the deepest levels of society, to become sustainable.
Anne van Veen, Ingrid Visseren-Hamakers
doaj   +1 more source

Green and Brown? Globalization and the Environment [PDF]

Globalization - viewed as a process of economic integration that embraces governance as well as markets - could lead to worldwide convergence toward higher or lower environmental quality, or to environmental polarization in which the 'greening' of the ...
James K. Boyce
core  

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source

The influence of public awareness on public participation in environmental governance: empirical evidence in China

Environmental Research Communications
Public participation in environmental governance is conducive to alleviating environmental pollution. To mobilize the enthusiasm of the public to participate in environmental governance, using nationwide Chinese General Social Survey (CGSS) samples on ...
Lisha Zhang, Mingyang Yue, Lingfei Qu, Biao Ren, Tao Zhu, Rong Zheng   +5 more
doaj   +1 more source

Governance and Environmental Policy Integration in Europe: What Can We learn from the EU Emission Trading Scheme? [PDF]

The European Union Emission Trading System (EU ETS) is a landmark environmental policy, representing the world’s first large-scale greenhouse gas (GHG) trading program.
Alessandra Sgobbi, Barbara Buchner, Michela Catenacci   +2 more
core  

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

Molecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu, Xixi Lin, Emil Mladenov, Veronika Mladenova, Jürgen Thomale, Ali Sak, Yao Wang, Yunxuan Deng, Eleni Gkika, Martin Stuschke, George Iliakis   +10 more
wiley   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Influencing factors and mechanisms of farmers’ participation in promoting the effect of rural environmental governance—a qualitative comparative analysis based on Chinese cases

Frontiers in Environmental Science
Introduction:Farmers’ participation is the key to promoting the good governance of the rural environment, but the discussion on the effectiveness of farmers’ participation in rural environmental governance is still weak.Methods:A “dynamic-process ...
Cheng Fu, Cheng Fu, Tianfeng Li, Lei Cao, Fujun Zhou   +4 more
doaj   +1 more source