Results 121 to 130 of about 820,522 (298)

Molecular cancer prevention: Intercepting disease

open access: yesMolecular Oncology, EarlyView.
Oncological practice must evolve, from treating established tumours to proactive cancer interception before clinical manifestation. This will require mechanistic insight into tumour initiation, validated biomarkers of early disease development and redesigned clinical trials, enabling cancer interception to become a core pillar of oncology with the ...
Charlotte Grieco   +2 more
wiley   +1 more source

Eco-government: a new approach to bureaucracy pathology challenges

open access: yesFrontiers in Political Science
Persistent bureaucratic pathologies—such as corruption, inefficiency, nepotism, and resistance to change—continue to undermine public sector performance in many countries.
Andi M. Rusli   +3 more
doaj   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

open access: yesMolecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary   +1 more
wiley   +1 more source

Embracing complexity in international forest governance: a way forward; Policy Brief [PDF]

open access: yes
This Policy Brief summarizes the findings of a comprehensive assessment of scientific information about international forest governance carried out by an Expert Panel of over 30 of the world's leading scientists working in the areas of environmental ...
Arts, B.J.M.   +8 more
core   +1 more source

DNA methylation and expression of MAPRE3 affect overall survival of early‐stage non‐small cell lung cancer patients

open access: yesMolecular Oncology, EarlyView.
Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen   +14 more
wiley   +1 more source

A Comprehensive Dataset of Factory Farms in California Compiled Using Computer Vision and Human Validation

open access: yesScientific Data
Concentrated Animal Feeding Operations (CAFOs) house livestock at high densities for prolonged periods of time, posing substantial risks to environmental and human health.
Varun Magesh   +8 more
doaj   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

open access: yesFEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz   +6 more
wiley   +1 more source

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