Results 171 to 180 of about 4,497,175 (353)

Inhibition of CDK9 enhances AML cell death induced by combined venetoclax and azacitidine

open access: yesMolecular Oncology, EarlyView.
The CDK9 inhibitor AZD4573 downregulates c‐MYC and MCL‐1 to induce death of cytarabine (AraC)‐resistant AML cells. This enhances VEN + AZA‐induced cell death significantly more than any combination of two of the three drugs in AraC‐resistant AML cells.
Shuangshuang Wu   +18 more
wiley   +1 more source

Environmental health 2000. [PDF]

open access: yesEnvironmental Health Perspectives, 1998
openaire   +2 more sources

Health-enhancing activities and the environment:How competition for resources make the environmental policy beneficial [PDF]

open access: yes
In a two-period overlapping generations model, this paper demonstrates that the relationship between environmental taxation and economic activity (output level and output growth) becomes inverted-U shaped when the detrimental impact of pollution on ...
Xavier Pautrel
core  

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

open access: yesMolecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié   +16 more
wiley   +1 more source

Evaluating a Research Training Program in Environmental Health and Noncommunicable Diseases in Georgia. [PDF]

open access: yesInt J Environ Res Public Health
Berg CJ   +8 more
europepmc   +1 more source

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