Results 191 to 200 of about 29,397,810 (306)

Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer

open access: yesMolecular Oncology, EarlyView.
Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim   +7 more
wiley   +1 more source

Environmental Health Resilience

open access: yesEnvironmental Health Insights, 2013
Tim Kelley
doaj  

Environmental, Health, and Social Consciousness as Drivers of Organic Food Choice. [PDF]

open access: yesNutrients
Escobar-Farfán M   +4 more
europepmc   +1 more source

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

open access: yesMolecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic   +10 more
wiley   +1 more source

Environmental public health practice and CDC\u2019s food safety winnable battle

open access: yes
Did you know that every year more than 1 in 6 Americans gets foodborne illness? And that more than half of all foodborne illness outbreaks in the United States are associated with restaurants?CDC is taking action to prevent these outbreaks by improving ...

core  

Environmental Health Hazardscapes

open access: yesEnvironmental Health Insights, 2013
Timothy Kelley, Michelle Covi
doaj  

The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer

open access: yesMolecular Oncology, EarlyView.
Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad   +2 more
wiley   +1 more source

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