Results 171 to 180 of about 29,397,810 (306)

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

open access: yesMolecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

Environmental Health Competency Questionnaire Report : Summary Results \u2022 February 22, 2021

open access: yes
During the summer of 2020, the Environmental Health & Equity Collaborative\u2019s Education and Workforce Committee undertook an assessment of current environmental health workforce needs related to specific knowledge, skills and competencies. Ultimately,

core  

Environmental public health tracking program; closing America's environmental public health gap, 2003 [PDF]

open access: yes
"Environmental public health tracking is the ongoing collection, integration, analysis, and interpretation of data about environmental hazards, exposure to environ mental hazards, and human health effects potentially related to exposure to environmental ...

core  

PANoptosis in the pathogenesis of myelodysplastic syndromes

open access: yesMolecular Oncology, EarlyView.
PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla   +4 more
wiley   +1 more source

Environmental health in crisis-who do we want to be? [PDF]

open access: yesJ Expo Sci Environ Epidemiol
Clougherty JE.
europepmc   +1 more source

Spatial biology in cancer epigenetics

open access: yesMolecular Oncology, EarlyView.
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley   +1 more source

National Center for Environmental Health at the turn of the century, 1999-2003 [PDF]

open access: yes
The National Center for Environmental Health (NCEH), as part of the Centers for Disease Control and Prevention (CDC), is unique in the federal government for its focus on public health issues related to the environment.

core  

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

open access: yesMolecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche   +10 more
wiley   +1 more source

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