Results 61 to 70 of about 795,117 (293)
Eating on the Eve of the Early Modern Period
Between 1485 and 1487, the Patriarch of Aquileia sent the bishop of Caorle (Italy) to the Alps-Adriatic region to re-consecrate churches, chapels, and cemeteries that had been desecrated during the Turkish invasions. Among the travelers was the bishop’s
Stephan F. Ebert
doaj +1 more source
Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee +7 more
wiley +1 more source
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley +1 more source
Finland: Environmental History in National Languages [PDF]
For some time, the journal Environment and History has published Notepad surveys on the development of the research on environmental history in the national languages. I was asked to work out a review of the recent trends in Finland.
Timo Myllyntaus
core
Design and analysis strategies for robust microbiome ageing research
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Reconstructing enzyme evolution by protein engineering
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Oceania: The environmental history of one-third of the globe
Oceania, the region encompassing the Pacific Islands, is the longest continually settled oceanic environment on our predominantly blue aquatic planet - for this reason alone, it deserves far greater attention than it receives.
D'Arcy, Paul
core +1 more source
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi +6 more
wiley +1 more source

