Results 91 to 100 of about 373,503 (305)

Agriculturización e impactos ambientales en un área representativa de la ecorregión de las pampas, argentina. [PDF]

open access: yes, 2014
Estudos prévios demonstram a existência do processo de agriculturização na ecorregião das Pampas, e o partido de Tandil constitui um exemplo desse processo.
Vazquez, Patricia Susana   +1 more
core  

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

open access: yesFEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

IMPACT: The Journal of the Center for Interdisciplinary Teaching and Learning. Volume 5, Issue 2, Summer 2016 [PDF]

open access: yes, 2016
Impact: The Journal of the Center for Interdisciplinary Teaching & Learning is a peer-reviewed, biannual online journal that publishes scholarly and creative non-fiction essays about the theory, practice and assessment of interdisciplinary education ...

core  

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

open access: yesMolecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice   +16 more
wiley   +1 more source

The Glorious Plagiarism, Trash Aesthetics, and Ecological Entropy of Cryptic Cut-Ups from Minutes to Go

open access: yesHumanities, 2019
This paper examines some of the many ways in which example early cut-ups from Minutes to Go recall canonical literary forms, revive the revolutionary destructive urgency of Dada aesthetics, as well as contribute to wider environmental concerns.
Chad Weidner
doaj   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

open access: yesMolecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak   +4 more
wiley   +1 more source

Lucky Aesthetics: Multinatural Perspectivalism and (Divinatory) Semiosis

open access: yesAustralian Journal of Environmental Education
This essay will describe the critical importance of developing a posthuman aesthetic pedagogy capable of integrating what Eduardo Kohn (2013) has described as multinatural perspectivalism in How Forests Think.
Rachel Holmes
doaj   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

open access: yesMolecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla   +10 more
wiley   +1 more source

Does Environmental Economics lead to patentable research?

open access: yes, 2019
In this feasibility study, the impact of academic research from social sciences and humanities on technological innovation is explored through a study of citations patterns of journal articles in patents.
Hu, Xiaojun   +2 more
core  

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