Results 71 to 80 of about 373,503 (305)

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Local Economies, Trade, and Global Sustainability [PDF]

open access: yes, 1999
Bioregional and "ecological economics" theory describes the growth of local economic linkages as vital to move post-industrial economies in the direction of sustainability.
Perkins, Patricia E. (Ellie)
core  

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Social diversity and the sustainability of community economies [PDF]

open access: yes, 1997
Economic restructuring related to globalization is producing a bifurcation in economic activity throughout the OECD countries: a split between those workers/industries/areas which are competitive in the global market, and those which are being phased out.
Perkins, Patricia E. (Ellie)
core  

Environmental Humanities [PDF]

open access: yesEnvironmental Humanities, 2020
Dolly Jørgensen, Franklin Ginn
openaire   +1 more source

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Borderless Boundaries – as Means of Death and Life: Wilderness Portraits in Patristic and Rabbinic Literature [PDF]

open access: yes, 2015
This study examines the role played by environmental representation of an apparent borderless boundary, the desert, as presented in Scripture – the Hebrew Bible / First Testament.
Maoz, Daniel
core   +2 more sources

Introduction: Environmental Humanities Approaches to Climate Change

open access: yesHumanities, 2020
The development of the environmental humanities as an interdisciplinary formation is a response to an ecological and planetary crisis [...]
David Higgins   +2 more
doaj   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

open access: yesFEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz   +11 more
wiley   +1 more source

Ecological Urbanism in a Single Place: Forest Management in Novosibirsk Akademgorodok in the 1960’s–1980’s

open access: yesHistoria provinciae: журнал региональной истории
The article examines the history of green space management in the Novosibirsk Scientific Center of the USSR Academy of Sciences (Akademgorodok). In order to identify methods for managing green spaces in Akademgorodok, the author analyzes the work of ...
Timofei N. Rakov
doaj   +1 more source

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