Results 71 to 80 of about 373,503 (305)
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Local Economies, Trade, and Global Sustainability [PDF]
Bioregional and "ecological economics" theory describes the growth of local economic linkages as vital to move post-industrial economies in the direction of sustainability.
Perkins, Patricia E. (Ellie)
core
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Social diversity and the sustainability of community economies [PDF]
Economic restructuring related to globalization is producing a bifurcation in economic activity throughout the OECD countries: a split between those workers/industries/areas which are competitive in the global market, and those which are being phased out.
Perkins, Patricia E. (Ellie)
core
Environmental Humanities [PDF]
Dolly Jørgensen, Franklin Ginn
openaire +1 more source
Diversity and complexity in neural organoids
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Borderless Boundaries – as Means of Death and Life: Wilderness Portraits in Patristic and Rabbinic Literature [PDF]
This study examines the role played by environmental representation of an apparent borderless boundary, the desert, as presented in Scripture – the Hebrew Bible / First Testament.
Maoz, Daniel
core +2 more sources
Introduction: Environmental Humanities Approaches to Climate Change
The development of the environmental humanities as an interdisciplinary formation is a response to an ecological and planetary crisis [...]
David Higgins +2 more
doaj +1 more source
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
The article examines the history of green space management in the Novosibirsk Scientific Center of the USSR Academy of Sciences (Akademgorodok). In order to identify methods for managing green spaces in Akademgorodok, the author analyzes the work of ...
Timofei N. Rakov
doaj +1 more source

