Results 201 to 210 of about 13,671,980 (384)
10.A. Workshop: Integration of health appraisal within urban planning and environmental impact assessments [PDF]
, 2017 Chairs: Odile Mekel, Germany, Arpana Verma, UK +1 more
openalex +1 more source
Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition
Molecular Oncology, EarlyView.We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li +10 more
wiley +1 more source
The economic and environmental factors of water in arid regions: Study of the rural water use in Northern Darfur Region, Sudan [PDF]
We develop hypothetical policy scenarios in this part of the paper which are simulated using a product-by-industry economic-ecological model to investigate their impacts on water and other ecological commodities. Results are expected to contribute to the
Mohamed, Issam A.W.
core +1 more source
Molecular Oncology, EarlyView.We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala +15 more
wiley +1 more source
Environmental impact of site location on macro- and microelements in Tansy
, 2010 Svetlana Stevovi +2 more
openalex +2 more sources
Product ecodesign and materials: current status and future prospects
, 2007 The aim of this paper is to discuss the current status of ecodesign in the industry and its future implications for materials. There is today more and more focus on the environmental impacts of products during their whole life cycle.
Brissaud, Daniel +2 more
core +2 more sources
Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Molecular Oncology, EarlyView.Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source
INTERNATIONAL ENVIRONMENTAL HEALTH: Assessing the Global Composite Impact of Chemicals on Health
, 2011 Bob Weinhold
openalex +2 more sources