Results 111 to 120 of about 431,544 (308)

The Challenge of Building Proper Urban Indicator System: A Proposal for Croatian Cities [PDF]

open access: yes
In this paper, urban indicator system is investigated in the context of urban policy processes. Indicators are seen as a tool to enhance urban management and special attention is given to their role in providing assistance in monitoring municipal ...
Zeljka Kordej De Villa   +1 more
core  

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

open access: yesMolecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano   +6 more
wiley   +1 more source

Report of the second national consultation workshop on agri-environmental indicators for Canadian agriculture

open access: yes, 1995
This report summarizes the results of the second national consultation workshop on agri-environmental indicators (AEIs) for Canadian agriculture, held in Fredericton, New Brunswick on 9 and 10 February 1995.
McRae, Terence
core  

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

A survey of the coverage, use and application of ancient woodland indicator lists in the UK

open access: yes, 2009
This report presents the results of a survey into the current use of ancient woodland indicator species lists in the UK. The idea of using species particularly vascular plants as indicators of ancient woodlands can be dated back to the 1970s and the work
Handley, Christine   +4 more
core  

Carbon Footprint Assessment of Construction Waste Packaging Using the Package-to-Product Indicator

open access: yes, 2020
The environmental impacts of buildings are based on the construction products, which together with their packaging can be assessed as one product system.
Markéta Šerešová   +2 more
core   +1 more source

Environmental performance assessment of Brazilian ports capable of operating post-panamax ships

open access: yesSustainable Futures
Ports are essential to Brazil’s economy, facilitating the export of agricultural products, minerals, and industrial goods. With 35 public ports and 175 private terminals, the country faces pressing challenges in modernizing its infrastructure to ...
Adriane Marques Pimenta   +4 more
doaj   +1 more source

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

open access: yesMolecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos   +6 more
wiley   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

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