Results 91 to 100 of about 5,624,280 (251)
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
Using oligochaeta assemblages as an indicator of environmental changes
We designed a field survey (the entire river length; not dammed: First and Second plateaus; dammed: Third Plateau) to test the hypothesis that the cascade of reservoirs promoted a reduction in species richness and changed the composition of Oligochaeta ...
RDL. Behrend +3 more
doaj +1 more source
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell +2 more
wiley +1 more source
Sustainable Development Indicator Frameworks and Initiatives [PDF]
Agricultural and Food Policy, Environmental Economics and Policy, Farm Management, Production Economics,
Deverre, Christian +3 more
core
‘Guide and Prejudice’— How Argonautes recognize targets across domains of life
Argonaute proteins use short nucleic‐acid guides to locate and regulate specific targets across all domains of life. Despite striking diversity—from human gene silencing to bacterial immune defence—all Argonautes share a conserved three‐stage recognition logic: guide‐directed sampling, progressive target pairing with a conformational checkpoint and ...
Jack P. K. Bravo
wiley +1 more source
A real-time recession indicator for the Euro area [PDF]
In this paper, we propose a new coincident monthly indicator to detect in real-time the start and the end of an economic recession phase for the Euro area.
Ferrara, Laurent
core
This research aims to analyze the effect of the Project-Based Learning theme Blue My Sky is Healthy My Earth to increase environmental literacy. The research carried out was quasi-experimental quantitative research using statistical tests on numerical ...
Tegar Sindu Wicaksono +2 more
doaj +1 more source
Structural and biochemical analysis of a B12 superbinder
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices +3 more
wiley +1 more source
A survey of the coverage, use and application of ancient woodland indicator lists in the UK [PDF]
This report presents the results of a survey into the current use of ancient woodland indicator species lists in the UK. The idea of using species particularly vascular plants as indicators of ancient woodlands can be dated back to the 1970s and the work
Handley, Christine +4 more
core +1 more source
Macrobenthic indicator species: From concept to practical applications in marine ecology
As marine ecosystems and habitats continue to degrade, scientists urgently need a simple and effective method to monitor and assess the ecological environment.
Wanhong Han, Qingxi Han
doaj +1 more source

