Results 131 to 140 of about 1,493,909 (303)
Nitrate Contamination of Groundwater: Determinants and Indicators [PDF]
Nitrogen is an important input to agricultural production but also detrimentally affects the environmental quality of air, soil and water. Identifying the determinants of nitrate pollution and in turn defining sensible performance indicators to design ...
Heumesser, Christine +2 more
core +1 more source
Environmental health indicators in policy evaluation [PDF]
, 2017 In carrying out two projects involving environmental health indicators - a national environmental health programme evaluation and an international environmental health indicator system - in parallel, it became apparent that an international indicator set
Braun-Fahrländer, Charlotte +1 more
core
Screening for lung cancer: A systematic review of overdiagnosis and its implications
Molecular Oncology, EarlyView.Low‐dose computed tomography (CT) screening for lung cancer may increase overdiagnosis compared to no screening, though the risk is likely low versus chest X‐ray. Our review of 8 trials (84 660 participants) shows added costs. Further research with strict adherence to modern nodule management strategies may help determine the extent to which ...
Fiorella Karina Fernández‐Sáenz +12 more
wiley +1 more source
Vegetation Dynamics Studies Based on Ellenberg and Landolt Indicator Values: A Review
LandUnderstanding the dynamics and system of interrelationships between habitats and plant communities is key to making reliable predictions about sustainable land use, biodiversity conservation and the risks of environmental crises.
Natalya Ivanova, Ekaterina Zolotova
doaj +1 more source
A proof of concept on real-time air quality monitoring system [PDF]
, 2017 According to the Department of Environment Malaysia, Air Pollutant Index (API) is an indicator for the air quality status at any particular area. API is calculated based on average concentration of air pollutants such as Sulphur Dioxide (SO2), Nitrogen ...
Ibrahim, Noraini +2 more
core
Survivin and Aurora Kinase A control cell fate decisions during mitosis
Molecular Oncology, EarlyView.Aurora A interacts with survivin during mitosis and regulates its centromeric role. Loss of Aurora A activity mislocalises survivin, the CPC and BubR1, leading to disruption of the spindle checkpoint and triggering premature mitotic exit, which we refer to as ‘mitotic slippage’.
Hana Abdelkabir +2 more
wiley +1 more source
Molecular Oncology, EarlyView.A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He +8 more
wiley +1 more source
Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA
Molecular Oncology, EarlyView.Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson +2 more
wiley +1 more source
Is Australia on a sustainability path? Interpreting the clues [PDF]
Genuine savings is a conceptually valid one-sided indicator as to whether Australia is on a weak sustainability path (negative GS would warn that current welfare is unsustainable).
Randall, Alan
core +1 more source
Molecular Oncology, EarlyView.HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto +13 more
wiley +1 more source