Results 161 to 170 of about 431,544 (308)

Faecal Source Tracking in Surface Waters: A Review of Faecal Indicator Microorganisms and Current Methods

open access: yes, 2005
Faecal indicator microorganisms have long been used by water quality industries to assess the quality of surface, ground and shellfish-harvesting waters.
Neller, Ron   +5 more
core  

Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function

open access: yesFEBS Open Bio, EarlyView.
We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke   +4 more
wiley   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

open access: yesFEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane   +11 more
wiley   +1 more source

Environmental pressure indicator for dispertion, evaluation report

open access: yes, 2003
This report describes in detail the assumptions and methodological choices during the development of an environmental pressure indicator based on the so-called distance-to-target (dtt) principle.
Brandes LJ, Bovenkamp A van de
core  

The skills required for transition to university and study in biological sciences: A student perspective

open access: yesFEBS Open Bio, EarlyView.
Bioscience students were asked for their opinions on the value and teaching of skills. 204 responded that teamwork, time management and study skills are necessary to reach University, that scientific writing, research, laboratory and presentation skills are taught effectively during their studies, while other skills are gained inherently through study ...
Janella Borrell, Susan Crennell
wiley   +1 more source

Environmental pressure indicator for dispertion, evaluation report

open access: yes, 2012
Dit rapport beschrijft de aannames en keuzes gemaakt tijdens de ontwikkeling van de milieudrukindicator verspreiding. Het doel van de milieudrukindicator is inzicht geven in de gevolgen van het milieubeleid op de milieudruk van prioritaire stoffen.
Brandes LJ, Bovenkamp A van de
core  

Suppression of lung adenocarcinoma migration through organelle alkalization by human lactoferrin – albumin fusion

open access: yesFEBS Open Bio, EarlyView.
This paper reveals how human lactoferrin–albumin fusion (hLF‐HSA) potently suppresses lung adenocarcinoma cell migration. hLF‐HSA upregulates NHE7, leading to Golgi alkalization, disruption of the Golgi secretome, downregulation of MMP1, and reversal of EMT. These findings suggest a novel Golgi‐targeting strategy to suppress cancer cell migration.
Hana Nopia   +3 more
wiley   +1 more source

Home - About - Disclaimer - Privacy