Results 131 to 140 of about 373,186 (262)

Rapid screening of staphylokinase protein variants using an unpurified cell‐free expression system

FEBS Open Bio, EarlyView.
An unpurified cell‐free protein synthesis (CFPS) platform enables rapid functional screening of staphylokinase variants. Direct plasminogen‐activation assays performed in microplate format provide real‐time activity readouts, allowing rapid identification and ranking of variants with improved or reduced fibrinolytic activity without protein ...
Maria Tomková, Veronika Hovanová, Jiri Damborsky, Erik Sedlák   +3 more
wiley   +1 more source

Combined 5‐aminolevulinic acid and ferric ammonium citrate treatment promotes hair follicle growth by activating dermal papilla cells

FEBS Open Bio, EarlyView.
5‐Aminolevulinic acid combined with ferric ammonium citrate (5‐ALA/FAC) stimulates dermal papilla cell activity and promotes hair follicle growth. The treatment enhances ERK and AKT signaling, increases hair‐inductive gene expression, and restores dermal papilla function suppressed by dihydrotestosterone and oxidative stress, resulting in enhanced hair
Han‐Wook Ryu, Eok‐Soo Oh, Sewoon Kim
wiley   +1 more source

Geospatial analysis of tuberculosis incidence in relation to socio-economic and environmental indicators in Romania. [PDF]

Front Public Health
Zabroski J, Peptenatu D, Mahler B, Soliman A, Gruia AK, Grecu A, Munteanu I, Bǎloi A.   +7 more
europepmc   +1 more source

Social, Economic and Environmental Indicators of Urban Sustainability in India

, 2021
Prajapati HR.
europepmc   +1 more source

Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function

FEBS Open Bio, EarlyView.
We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke, Michal Banasik, Rokas Juodeikis, Martin J. Warren, Richard W. Pickersgill   +4 more
wiley   +1 more source

Invisible Gaps: Reflections on Microbial Exposure Pathways and the Limits of Environmental Indicators. [PDF]

Environ Health (Wash)
Thanchonnang C, Rattanapitoon SK, Padchasuwan NH, Rattanapitoon NK.   +3 more
europepmc   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

Dataset on bus mobility and environmental indicators from Rio de Janeiro. [PDF]

Sci Data
Carvalho D, Vancellote V, Casais PM, Carabetta JL, Almeida B, Porto F, Mendes E, Souza RR, Cardoso DO, Wanke PF, Barbastefano R, Coutinho R, Brandão D, Diaz-Cacho M, Mendes A, Ogasawara E.   +15 more
europepmc   +1 more source

The skills required for transition to university and study in biological sciences: A student perspective

FEBS Open Bio, EarlyView.
Bioscience students were asked for their opinions on the value and teaching of skills. 204 responded that teamwork, time management and study skills are necessary to reach University, that scientific writing, research, laboratory and presentation skills are taught effectively during their studies, while other skills are gained inherently through study ...
Janella Borrell, Susan Crennell
wiley   +1 more source

Geographical distribution and the impact of socio-environmental indicators on incidence of Mpox in Ontario, Canada. [PDF]

PLoS One
Ugwu CLJ, Asgary A, Wu J, Kong JD, Bragazzi NL, Orbinski J, Woldegerima WA.   +6 more
europepmc   +1 more source