Weak and strong sustainability indicators, and regional environmental resources [PDF]
Many attempts to operationalize the ecological concept of sustainability have been undertaken by the economics profession during recent years. It seems that many mainstream economists tend to focus their research on the assumption of substitutability ...
Michael Kosz
core
Current, emerging and future technologies for sensing the environment [PDF]
, 2009 This paper reviews current technologies that are used for environmental monitoring, and presents emerging technologies that will dramatically improve our ability to obtain spatially distributed, real-time data about key indicators of environmental ...
Diamond, Dermot
core
Molecular Oncology, EarlyView.This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert +13 more
wiley +1 more source
Inhibition of CDK9 enhances AML cell death induced by combined venetoclax and azacitidine
Molecular Oncology, EarlyView.The CDK9 inhibitor AZD4573 downregulates c‐MYC and MCL‐1 to induce death of cytarabine (AraC)‐resistant AML cells. This enhances VEN + AZA‐induced cell death significantly more than any combination of two of the three drugs in AraC‐resistant AML cells.
Shuangshuang Wu +18 more
wiley +1 more source
A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression
Molecular Oncology, EarlyView.Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak +8 more
wiley +1 more source
Evaluation of hair and nail cortisol concentrations and associations with behavioral, physical, and environmental indicators of chronic stress in cats. [PDF]
J Vet Intern Med, 2021 Contreras ET +3 more
europepmc +1 more source
Quantitative Analysis of the Impact of Agricultural Management Strategies on Environmental Indicators [PDF]
This study uses an integrated economic-environmental modeling system to provide quantitative estimates that were used in the process of setting provincial environmental outcome targets under the APF.
Heigh, Lori, Junkins, Bruce
core +1 more source
Molecular Oncology, EarlyView.Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié +16 more
wiley +1 more source
Ageing Well in Small Villages: What Keeps Older Adults Happy? Environmental Indicators of Residential Satisfaction in Four Dutch Villages. [PDF]
Int J Environ Res Public Health, 2022 Moor NJA, Hamers K, Mohammadi M.
europepmc +1 more source
Looking for the (missing) indicators of social sustainability - Evidence from sustainability standards in the coffe sector [PDF]
, 2010 Rising consumer interest for ethical and/or responsible products and the growing interweaving of social and environmental issues question the ability of scientific methods to correctly assess social impacts. To this day however, no consensus has yet been
Lemeilleur, Sylvaine, Vagneron, Isabelle
core