Aggressive prostate cancer is associated with pericyte dysfunction
Molecular Oncology, EarlyView.Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero +11 more
wiley +1 more source
Developing procedures for assessment of ecological status of Indian River basins in the context of environmental water requirements [PDF]
River basins / Ecology / Indicators / Environmental flows / Environmental management / Habitats / Biota / Fish / Ecosystems / India / Krishna River Basin / Chauvery River Basin / Narmada River Basin / Periyar River Basin / Ganga River ...
Arunachalam, M. +8 more
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Screening for lung cancer: A systematic review of overdiagnosis and its implications
Molecular Oncology, EarlyView.Low‐dose computed tomography (CT) screening for lung cancer may increase overdiagnosis compared to no screening, though the risk is likely low versus chest X‐ray. Our review of 8 trials (84 660 participants) shows added costs. Further research with strict adherence to modern nodule management strategies may help determine the extent to which ...
Fiorella Karina Fernández‐Sáenz +12 more
wiley +1 more source
Survivin and Aurora Kinase A control cell fate decisions during mitosis
Molecular Oncology, EarlyView.Aurora A interacts with survivin during mitosis and regulates its centromeric role. Loss of Aurora A activity mislocalises survivin, the CPC and BubR1, leading to disruption of the spindle checkpoint and triggering premature mitotic exit, which we refer to as ‘mitotic slippage’.
Hana Abdelkabir +2 more
wiley +1 more source
2006 State of the Estuaries Report [PDF]
, 2006 The 2006 State of the Estuaries Report includes twelve indicators intended to report on the health and environmental quality of New Hampshire’s estuaries.The New Hampshire Estuaries Project (NHEP) developed and now implements a Monitoring Plan to track ...
New Hampshire Estuaries Project
core +2 more sources
Rapid coral reef assessment using 3D modelling and acoustics: acoustic indices correlate to fish abundance, diversity and environmental indicators in West Papua, Indonesia. [PDF]
PeerJ, 2021 Peck M +3 more
europepmc +1 more source
The Rural Economy Research Centre [PDF]
, 2006 End of project report ENARPRIThe economic impact of trade policy reform receives less attention than the impact of trade policy on the environment. In part this may be due to the secondary importance attributed to environmental issues when economic ...
Donnellan, Trevor, Hanrahan, Kevin
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Molecular Oncology, EarlyView.A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He +8 more
wiley +1 more source
Institutions in transition : reliability of rules and economic performance in former Socialist countries [PDF]
Building reliable institutions that support a market system is widely believed to be critical to a successful economic transition. The authors present indicators on the predictability of the institutional framework across twenty transition economies ...
Brunetti, Aymo +2 more
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Environmental capacity in the East Midlands: an evidence base fit for purpose [PDF]
, 2008 This report relates to the initial study into the measurement of Environmental Capacity within the East Midlands Region considering what indicators/measures of Environmental Capacity can be put into place in the near future within the region and what are
Glaves, Peter +3 more
core