Results 51 to 60 of about 373,186 (262)

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

open access: yesFEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz   +11 more
wiley   +1 more source

Effects of jackfruit (Artocarpus heterophyllus) on the epigeal fauna community and litter in Atlantic Forest areas [PDF]

open access: yesCiência Rural
: The soil-litter interface represents a fundamental habitat for numerous invertebrate organisms that perform crucial ecological functions and are used as indicators of environmental quality. This study evaluated the impact of jackfruit trees (Artocarpus
Deivid Lopes Machado   +3 more
doaj   +2 more sources

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

open access: yesFEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil   +4 more
wiley   +1 more source

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

open access: yesFEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

Environmental heterogeneity: Anuran diversity in homogeneous environments

open access: yesZoologia (Curitiba), 2011
The northwestern region of São Paulo was extensively deforested during the agricultural expansion in the last century and only small fragments of the original vegetation cover remained.
Rodrigo Augusto Silva   +2 more
doaj   +1 more source

The human gut microbiome across the life course

open access: yesFEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero   +4 more
wiley   +1 more source

Evaluation of Portland pozzolan blended cements containing diatomaceous earth

open access: yesCerâmica
Clinker replacement by supplementary cementitious materials (SCMs) is one strategy to reduce CO2 emissions of cement industry. Diatomaceous earth, a natural pozzolan, has been used as SCM.
P. C. R. A. Abrão   +2 more
doaj   +1 more source

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

open access: yesFEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas   +6 more
wiley   +1 more source

Meta-Analysis and MaxEnt Model Prediction of the Distribution of Phenacoccus solenopsis Tinsley in China under the Context of Climate Change

open access: yesInsects
Phenacoccus solenopsis Tinsley is a pest that poses a significant threat to agricultural crops, especially cotton, and is now widely distributed across many regions worldwide. In this study, we performed a meta-analysis on the collected experimental data
Zhiqian Liu   +3 more
doaj   +1 more source

Historical Analysis of EPI in Colombia (2006-2014): Challenges on Environmental Information

open access: yesGestión y Ambiente, 2019
The use of environmental indicators has been established as a way of addressing different variables and objects of analysis, including the complexity of biodiversity and ecosystems along with human wellbeing.
Ana María González   +1 more
doaj   +1 more source

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