Results 81 to 90 of about 6,227,014 (305)
The microbiome in human skin aging
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana +3 more
wiley +1 more source
The travertine profiles are located in the Zhaga waterfall in Munigou, Sichuan Province, where the highest altitude ranges from 4,070 m to 2,800 m, and the average annual temperature is 7℃.
Jingwen HE +8 more
doaj +1 more source
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source
EXPERT SYSTEMS FOR ENVIRONMENTAL PROTECTION IN MINING
Expert systems are used in various activities with the main goal of decision-making in intelligent and transparent way. In business decision-making, such systems are directed to pure operational and economical decisions.
Damir Rumenjak
doaj
Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source
Aligning rural credit with sustainable practices: environmental indicators for agricultural policies
This study examines the interface between rural credit policies and environmental sustainability objectives in Brazil, focusing on the 2023/2024 Harvest Plan and the 2024–2027 Pluriannual Plan (PPA). The analysis reveals that, despite normative advances,
Luis Eduardo Pacifici Rangel +7 more
doaj +1 more source
Children's Environmental Health Indicators in Australia
Adverse environmental exposures in early life increase the risk of chronic disease but do not attract the attention nor receive the public health priority warranted. A safe and healthy environment is essential for children's health and development, yet absent in many countries.
Sly, J. Leith +6 more
openaire +6 more sources
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
Environmental and wider economic implications of modifications to environmental tax reform [PDF]
The most common definition of Environmental Tax Reform (ETR) is the use of the revenue from environmental taxes to reduce distortionary labour taxes. However, the PETRAS project has shown that there are a number of social and political impediments to ...
Clinch, J. Peter, Dunne, Louise
core +1 more source
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell +2 more
wiley +1 more source

