Results 71 to 80 of about 21,210,125 (249)
Environmental Information Portals, Services, and Retrieval Systems
Environmental Information (EI) accounts for the majority of public sector information in Europe, and poses a considerable potential for added value services via its customisation and re-use.
Karatzas, Kostas +2 more
core +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
In the last years the environmental awareness has strengthened because of the rareness or destruction of natural resources, increase of the costs as well as environmental problems and environmental impacts.
Rezgui, Abdelkerim, Naana, Miada
core +1 more source
Access to environmental information. Role of Aarhus Convention
The article analyzes the existing legal acts of the Republic of Kazakhstan in the sphere of environmental protection and enforcement mechanisms of the legislation in this field, the role and mechanisms of the Aarhus Convention.
G K Rakhimzhanova
doaj
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source
Digital Soil Information System for Ireland – Scoping Study [PDF]
This synthesis report has been prepared as part of the Environmental Research Technological Development and Innovation (ERTDI) Programme under the Productive Sector Operational Programme 2000-2006. This programme is financed by the Irish Government under
Fealy, Reamonn, Daly, Karen M.
core +1 more source
Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
Assessing and managing potential health and safety issues related to high voltage direct current transmission lines [PDF]
The following report looks at assessing and managing potential health safety issues related to high voltage direct current transmission lines. The report includes information on HVDC transmission lines, HVDC electrical environment, biological effects of ...
Environmental Research Information, Inc.
core +3 more sources
Emerging experimental and computational methods for studying redox‐regulated structural transitions
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source

