Results 131 to 140 of about 2,842,568 (349)

Bio-communication of Plants [PDF]

open access: yes, 2007
Plants communicate with a great variety of symbiotic partners, above and below ground. Constant monitoring of signals of biotic origin as well as abiotic environmental influences allows plants to generate appropriate response behavior.
Guenther Witzany
core   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

open access: yesMolecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova   +14 more
wiley   +1 more source

Evaluating the 2023–2024 record dry-hot conditions in the Amazon in the context of historical compound extremes

open access: yesEnvironmental Research Letters
Since 2023, the Amazon rainforest has experienced unprecedented compound drought and heatwaves (CDHW). These events are closely linked to low soil moisture (SM) and high vapor pressure deficit (VPD), and have significant impacts on the Amazon ecosystem ...
Vanessa Ferreira   +4 more
doaj   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau   +8 more
wiley   +1 more source

Dynamic environmental interactions shaped by vegetative plant volatiles. [PDF]

open access: yesNat Prod Rep, 2023
Escobar-Bravo R   +3 more
europepmc   +1 more source

Environmental Labeling and Technology Adoption in the Presence of Strategic Interactions [PDF]

open access: yes
This manuscript analyzes the effect of binary ecolabeling on the strategic competition of Cournot duopolists in environmental technology and the output market.
Konishi, Yoshifumi
core   +1 more source

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