Results 231 to 240 of about 1,266,861 (312)

Multifunctional Gold Nanocluster‐Based PROTAC System for Targeted Degradation of Phosphorylated Tau and Modulation of Neuroinflammation in Alzheimer's Disease

open access: yesAdvanced Functional Materials, EarlyView.
We present a novel proteolysis‐targeting chimera (PROTAC) system conjugated to lipoic acid gold nanoclusters (PLANC), designed to degrade pTau, regulate inflammatory signaling, and effectively traverse the blood‐brain barrier (BBB). PLANC degraded pTau at various phosphorylation sites, with mechanistic studies confirming proteasome‐mediated degradation
Sarah Nevins   +9 more
wiley   +1 more source

Detection of pathogenic leptospires in water bodies in neighborhoods vulnerable to flooding, through a participatory research approach in Santa Fe (Argentina). [PDF]

open access: yesPLOS Glob Public Health
Carletti JV   +8 more
europepmc   +1 more source

Reduced Graphene Oxide Transparent Electrodes Enabling Compact Soft Tunable Lenses

open access: yesAdvanced Functional Materials, EarlyView.
By spray‐coating an elastomeric membrane with reduced graphene oxide (rGO) at various surface densities, elastomeric actuators are manufactured. Electro‐mechano‐optical characterizations show the suitability of rGO as an effective material for compliant, semi‐transparent electrodes, enabling soft electrically tunable lenses with a compact form factor ...
Giacomo Sasso   +4 more
wiley   +1 more source

Time‐Resolved Magnetization Switching Dynamics Driven by Orbital Torques

open access: yesAdvanced Functional Materials, EarlyView.
Du et al. reveal nanosecond magnetization switching driven by orbital currents using time‐resolved Hall detection. The measurements separate domain nucleation from domain wall propagation and show that Joule heating strongly assists switching by lowering energy barriers.
Ao Du   +4 more
wiley   +1 more source

Is It Real Type‐II or S‐Scheme? A Three‐Phase Diagnostic Protocol for Identifying Potentially Mislabeled Heterojunction Photocatalysts

open access: yesAdvanced Functional Materials, EarlyView.
Diagnostic analysis via the heterojunction validation funnel. The funnel illustrates the hierarchical stratification of 30 reported Type‐II systems based on the three‐phase, seven‐step diagnostic framework. Complete validation through all phases is achieved by only 3.3% of systems, while 96.7% lack full mechanistic validation, revealing a pervasive ...
Ki‐Hyun Kim
wiley   +1 more source

Co‐Electrospinning Extracellular Matrix with Polycaprolactone Enables a Modular Approach to Balance Bioactivity and Mechanics of a Multifunctional Bone Wrap

open access: yesAdvanced Healthcare Materials, EarlyView.
The incorporation of nondigested ECM and synthetic polymers into a co‐electrospinning system enables the decoupling of bioactivity and mechanical properties within a single wrap. This technique is used to develop a multifunctional bone wrap that achieves augmented membrane durability, sustained infection control, and enhanced vascularity for use in ...
Sarah Jones   +14 more
wiley   +1 more source

Assessment of knowledge and perceptions of health professionals towards One Health in Somaliland. [PDF]

open access: yesFront Vet Sci
Yusuf YM   +6 more
europepmc   +1 more source

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