Results 51 to 60 of about 1,006,388 (268)

Students' Environmental Knowledge Learning in the Era of Industrial Society 4.0 Reviewed from Digital Literacy Capability

Journal of Education Technology
The challenge of learning environmental knowledge in the era of industrial society 4.0 amidst the implementation of hybrid learning is low digital literacy capability.
Rahmatulloh, Napis
doaj   +1 more source

Discerning protein pools by selective staining with self‐labeling tags

FEBS Letters, EarlyView.
Cell surface proteins have an intra‐ and extracellular pool. Combining genetic fusion to self‐labeling tags that can be addressed with small molecule fluorophores allows separating these pools. We highlight recent developments and techniques for state‐of‐the‐art interrogation of cell surface proteins in the complex tissue setting.
Kati Fischermanns, Johannes Broichhagen
wiley   +1 more source

Environmental Knowledge and Deliberative Democracy

, 2010
In recent years deliberative democracy has spread to a remarkable pace in environment-related policy-making, affecting especially the way democracy meets scientific expertise. Science has for long time been understood as the social enterprise specialized in producing explanatory and predictive knowledge.
openaire   +4 more sources

Knowledge translation in Arctic environmental health [PDF]

International Journal of Circumpolar Health, 2012
In April 2012, the circumpolar research community gathered in Montre´al, Canada, to discuss their most recent research findings related to the International Polar Year (IPY). The conference was titled From Knowledge to Action, and its organisation and structure emphasised the importance of transmission of new knowledge generated by IPY projects to a ...
Eric Dewailly, Chris Furgal
openaire   +3 more sources

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Environmental Knowledge and Willingness to Act Pro-environmentally: Final Remarks

This book leverages data from two major international large-scale assessments—the Trends in International Mathematics and Science Study (TIMSS) 2019 and the International Civic and Citizenship Education Study (ICCS) 2016—to investigate the extent to which education for sustainable development learning outcomes, such as environmental knowledge and ...
Isac, Maria Magdalena, Sass, Wanda, Sandoval-Hernández, Andrés   +2 more
openaire   +2 more sources

ZW4864‐mediated inhibition of the β‐catenin/BCL9/BCL9L complex reveals therapeutic potential in bladder cancer

Molecular Oncology, EarlyView.
BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi, Mandy Berndt‐Paetz, Eileen Lerner, Gregoire Najjar, Anca Azoitei, Krishna Pal Singh, Shailendra Kumar Gupta, Olaf Wolkenhauer, Cagatay Günes, Otmar Huber, Marc‐Oliver Grimm, Daniel Steinbach   +11 more
wiley   +1 more source

Linking energy behaviour, attitude and habits with environmental predisposition and knowledge

International Journal of Sustainable Energy, 2017
The purpose of this paper is to present and discuss the findings of an empirical study that compares individuals' environmental predisposition and knowledge with their energy behaviour, attitude and habits.
Mary Pothitou, Liz Varga, Athanasios J. Kolios, Sai Gu   +3 more
doaj   +1 more source

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

Molecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source