Results 31 to 40 of about 5,566,878 (300)
FEBS Letters, EarlyView.Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source
Fragmentation, counter-power and symbiosis: The Life After Coal campaign
Journal of Political EcologySouth Africa's environmental movement has been described as "fractured, disparate and diverse" (Death, 2014: 1232). This article considers the Life After Coal campaign's work in eMalahleni, Mpumalanga to examine the challenges faced by environmental ...
Andries Motau, Shauna Mottiar
doaj +2 more sources
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Urban Environmental Justice Movements in the United States
, 2023 Some of America's most severe environmental inequalities occur in its cities. This was especially the case in the decades immediately following World War Two, when white flight, deindustrialization and disinvestment, urban renewal and highway ...
Gioielli, Robert R,
core +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Technical note: Stochastic simulation of streamflow time series using phase randomization [PDF]
Hydrology and Earth System Sciences, 2019 Stochastically generated streamflow time series are widely used in water resource planning and management. Such series represent sets of plausible yet unobserved streamflow realizations which should reproduce the main characteristics of observed data ...
M. I. Brunner, A. Bárdossy, R. Furrer
doaj +1 more source
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
FEBS Letters, EarlyView.The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
Social Metabolism and Environmental Conflicts in India
Indialogs: Spanish Journal of India Studies, 2014 This paper explains the methods for counting the energy and material flows in the economy, and gives the main results of the Material Flows for the economy of India between 1961 and 2008 as researched by Simron Singh et al (2012). Drawing on work done in
Joan Martinez-Alier +2 more
doaj +1 more source
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source