Results 41 to 50 of about 5,566,878 (300)

Structure‐forward targeting of claudins with synthetic binders

FEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

The Politics of Environmental Networks

Politics and Governance
Environmental political networks research uses social network analysis to investigate the political processes underlying the complex relational dynamics of environmental governance.
Monica Di Gregorio, Petr Ocelík, Carlos Bravo-Laguna, Eva Fernández G.   +3 more
doaj   +1 more source

“No meu quintal, não!”. Contributos para uma análise dos movimentos ambientais de raiz popular em Portugal (1974-1994)

Revista Crítica de Ciências Sociais, 2003
The main purpose of this text is to provide an overview of grassroots environmental action in Portugal between 1974 and 1994, taking into account the principal contours of grassroots movements, as well as their articulation with the more global features ...
Elisabete Figueiredo, Teresa Fidélis
doaj   +1 more source

Epigenetic reprogramming of lineage switching in cancer

FEBS Letters, EarlyView.
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı, Burcu Akman, Ezgi Bağırsakçı, Nese Atabey, Serap Erkek‐Ozhan   +4 more
wiley   +1 more source

Analysis of the dynamics of environmental movements in France; Emphasizing the concept of ecological citizenship [PDF]

رهیافتهای سیاسی و بین المللی
Introduction and objectives: This article examines how environmental movements in France interact with their global counterparts and emphasizes the importance of cross-border cooperation and shared responsibility in addressing environmental challenges ...
maryam yari estahbanati, Bahare Sazmand
doaj   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

FEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass, Dana Reichmann, Gábor Erdős   +2 more
wiley   +1 more source

Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding

FEBS Letters, EarlyView.
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança, Eline L. Jansen, Jorine M. Eeftens   +2 more
wiley   +1 more source

Experiences of environmental professionals in practice [PDF]

, 2011
Purpose: The purpose of this paper is to explore the labor market position of environmental science graduates and the core competencies of these environmental professionals related to their working practice.
Bootsma, M.C., Bootsma, M., Environmental Governance, Margien Bootsma, Walter Vermeulen, Section Environmental Sciences, Vermeulen, W.J.V., Vermeulen, W., Section Environmental Governance, Environmental Sciences   +9 more
core   +2 more sources

Relational Processes and Networks in Environmental Politics

Politics and Governance
The inherently relational nature of environmental politics has stimulated the growth of network-oriented research. This concluding commentary emphasizes relationality in environmental political processes as central to understanding multilevel, multi ...
Eva Fernández G., Monica Di Gregorio, Carlos Bravo‐Laguna, Petr Ocelík   +3 more
doaj   +1 more source

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

FEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source