Results 71 to 80 of about 5,566,878 (300)
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Environmental Movements in Taiwan
[[sponsorship]]社會學研究所[[note]]已出版;有審查制度 ...
Hsiao, Hsin-Huang Michael
core
Is there a global environmental justice movement?
One of the causes of the increasing number of ecological distribution conflicts around the world is the changing metabolism of the economy in terms of growing flows of energy and materials. There are conflicts on resource extraction, transport and waste disposal. Therefore, there are many local complaints, as shown in the Atlas of Environmental Justice
Martinez-Alier, Joan +3 more
openaire +2 more sources
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober +16 more
wiley +1 more source
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
The British environmental movement: The development of an environmental consciousness and environmental activism, 1945-1975 [PDF]
This work investigates the development of an environmental consciousness and environmental activism in Britain, 1945-1975. The 1970s have been described as ‘the decade of the environment’ and was the period when the modern environmental movement emerged.
Wilson, Mark
core
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley +1 more source
Ohio Environmental Education Fund State Fiscal Year 2021 agenda
"March 2020."Grant programs -- Environmental science and engineering career initiatives -- Water quality education and monitoring by students and citizens -- ContactThis fact sheet summarizes the SFY21 annual plan of the office of Environmental Education
Ohio EPA. Office of Environmental Education
core
River defence and restoration movements: A literature review
Since the 1980s, scholars have been documenting protest movements against the building of large hydropower dams. These movements have arisen mainly in communities where people have experienced displacement and loss of livelihood without receiving ...
Jeroen Vos
doaj

