Results 51 to 60 of about 76,541 (297)

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

open access: yesMolecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova   +14 more
wiley   +1 more source

Case Study of the Environmental Noise and its Perception in the City of Cluj-Napoca, Romania

open access: yesArchives of Acoustics, 2020
The noise perceiving issue is very subjective and depends on several factors, such as: the living environment in which each person has grown and developed, the education they have received, the culture in which their life principles have formed and, last
Diana Ioana POPESCU
doaj   +1 more source

Impact of road traffic noise on annoyance and preventable mortality in European cities: A health impact assessment

open access: yesEnvironment International, 2022
Background: Road traffic is the main source of environmental noise in European cities and one of the main environmental risks to health and wellbeing. In this study we aimed to provide an in-depth assessment of available road traffic noise data and to ...
Sasha Khomenko   +12 more
doaj   +1 more source

A good practice guide on the sources and magnitude of uncertainty arising in the practical measurement of environmental noise [PDF]

open access: yes, 2007
A brief introduction to measurement uncertainty, uncertainty budgets, and inter-comparison exercises (repeated measurements), is provided in Chapter 2.
Craven, N.J., Kerry, G
core  

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

open access: yesFEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei   +3 more
wiley   +1 more source

Valuation of aircraft noise by time of day: a comparison of two approaches [PDF]

open access: yes, 2006
This paper reports an innovative application of stated preference techniques to derive values of aircraft noise by time of day and day of week. Revealed preference techniques cannot provide such segmentations which would clearly be of use in policy ...
Abigail L. Bristow   +5 more
core   +2 more sources

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

open access: yesFEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill   +4 more
wiley   +1 more source

People exposed to traffic noise in european agglomerations from noise maps. A critical review

open access: yesNoise Mapping, 2014
Two of the main objectives of the European Directive on environmental noise are, firstly, to unify acoustic indices for assessing environmental noise and, secondly, to standardize assessment methodologies.
Arana Miguel   +2 more
doaj   +1 more source

Noise assessment of the small-scale wind farm [PDF]

open access: yesE3S Web of Conferences, 2019
The importance of renewable energy and especially of eolian systems is growing. For this reason, we propose the investigation of an important pollutant - the noise, which has become so important that European Commission and European Parliament introduced
Alionte Cristian-Gabriel   +1 more
doaj   +1 more source

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