Results 61 to 70 of about 972,545 (266)

Design of Greenhouse Environmental Parameters Prediction System [PDF]

open access: yes, 2011
This paper designs an environmental parameters prediction system based on web for greenhouse. The system is designed using the MVC framework, and includes monitoring module and prediction module. The system can obtain the main environmental parameters from sensors, such as light, temperature, humidity, CO2 and so on.
Haokun Zhang, Heru Xue
openaire   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

Genetic parameters for birthweight environmental variability in mice

open access: yesJournal of Animal Breeding and Genetics, 2012
SummaryData from a divergent experiment for birthweight (BrW) environmental variability were used to estimate genetic parameters forBrWtrait and its environmental variability by fitting both homoscedastic (HO) and heteroscedastic (HE) models. A total of 5 475 records ofBrWfrom animals born from inbred dams, and 7 140 pedigree records were used.
Pun, A.   +6 more
openaire   +4 more sources

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

Impact of Environmental Parameters on Marathon Running Performance

open access: yesPLoS ONE, 2012
The objectives of this study were to describe the distribution of all runners' performances in the largest marathons worldwide and to determine which environmental parameters have the maximal impact.We analysed the results of six European (Paris, London, Berlin) and American (Boston, Chicago, New York) marathon races from 2001 to 2010 through 1,791,972
El Helou, Nour   +7 more
openaire   +5 more sources

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

Land‐use in Europe affects land snail assemblages directly and indirectly by modulating abiotic and biotic drivers

open access: yesEcosphere, 2019
Type and intensity of land‐use vary in space and time and strongly contribute to changes in richness and composition of species communities. In this study, we examined land snail communities in forests and grasslands in three regions of Germany. We aimed
Katja Wehner   +5 more
doaj   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

open access: yesMolecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova   +14 more
wiley   +1 more source

Rotifer Diversity in Botswana with an Analysis of Functional–Morphological Traits Along a Latitudinal Gradient in Africa and Europe

open access: yesDiversity
Afrotropical inland waters remain poorly studied for rotifer diversity. Here, we provide new distribution data from Botswana and connect these local patterns to continental-scale biogeography using an Africa–Europe occurrence dataset.
Radoslav Smolak   +4 more
doaj   +1 more source

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

open access: yesMolecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera   +11 more
wiley   +1 more source

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